National Institutes of Health

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In the Journals

Black patients at higher risk for cancer-associated venous thromboembolism

December 30, 2019
Black patients with cancer appeared to be at a higher risk for cancer-associated venous thromboembolism than patients of other races, according to…
Point/Counter

Should physicians prescribe antivirals to patients at high risk for flu-related complications more than 2 days after symptom onset?

Infectious Diseases in Children, December 2019
The release of the latest iteration of the Infectious Diseases Society of America guidelines on the management of influenza are a welcome addition…
FDA News

FDA advisory committee supports approval of Keytruda for high-risk bladder cancer

December 17, 2019
An FDA advisory committee today voted to support approval of pembrolizumab for the treatment of patients with bacillus Calmette-Guérin-unresponsive…
In the Journals

Sustained weight loss lowers risk for breast cancer

December 17, 2019
Women aged 50 years and older who had sustained weight loss over more than 8 years demonstrated a decreased risk for breast cancer compared with…
FDA News

FDA panel narrowly supports approval of maintenance olaparib in BRCA-mutated pancreatic cancer

December 17, 2019
An FDA panel today supported approval of olaparib as maintenance treatment for adults with deleterious or suspected deleterious germline…

Partnership funds research to assess connection between cancer, aging

December 2, 2019
The Partnership for Aging and Cancer Research Program awarded seven grants intended to fund research into the link between aging and cancer. The…
Cover Story

Near the Nation’s Capital Lies a ‘House of Hope’

Cell Therapy Next, November/December 2019
Chimeric antigen receptor T-cell therapies have been approved by the FDA for two indications thus far, with a third for multiple myeloma expected…
Feature

Cancer incidence not always the best measure of cancer trends

November 18, 2019
Cancer incidence rates represent one key measure of progress in the fight against cancer, but they are not the only consideration. According to a…

NIH selects five Lasker Clinical Research Scholars

November 16, 2019
The NIH selected five scientists as Lasker Clinical Research Scholars. The competitive program — part of a joint initiative with Albert and…
Feature

Access to care among ‘critical priorities’ for American Cancer Society’s new chief medical, scientific officer

October 28, 2019
William G. Cance, MD, has begun his new role as American Cancer Society’s chief medical and scientific officer. Cance, who started in…
Feature

NCI-sponsored clinical trials cost-effective, ‘practice influential’

October 22, 2019
A study by the NCI-sponsored SWOG Cancer Research Network showed nearly half of the network’s phase 3 clinical trials influenced clinical care…
In the Journals

Malnutrition common among older patients with cancer

October 10, 2019
Hospitalized older patients with cancer demonstrated higher risk for malnutrition compared with their younger counterparts, according to results of a…
Clinical Trials Snapshot

T-cell Responses to Concurrent HIV and Herpesvirus Infections

Cell Therapy Next, October/November 2019
An observational, prospective cohort study to discover new information about how HIV and herpes viruses interact with the immune system, with a goal…
Clinical Trials Snapshot

TCR-engineered T Cells in Solid Tumors (ACTengine)

Cell Therapy Next, October/November 2019
Phase 1 study evaluating the safety and tolerability of genetically modified autologous T cells expressing a T-cell receptor recognizing a…
Clinical Trials Snapshot

NY-ESO-1 TCR Engineered T Cell and HSC After Melphalan Conditioning Regimen in Treating Participants with Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Cell Therapy Next, October/November 2019
Phase 1, open-label study evaluating the safety and efficacy of adoptive transfer of autologous NY-ESO-1 CD8-TCR engineered T cells and NY-ESO-1…
Clinical Trials Snapshot

HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Cell Therapy Next, October/November 2019
Phase 1 study to determine the safety and feasibility of using HERV-E TCR-transduced autologous T Cells in patients with metastatic clear-cell…
Clinical Trials Snapshot

HA-1 T TCR T Cell Immunotherapy for the Treating of Patients with Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Cell Therapy Next, October/November 2019
Phase 1 study of adoptive immunotherapy with CD8+ and CD4+ memory T cells transduced to express an HA-1-specific T cell receptor for children and…
Clinical Trials Snapshot

Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes

Cell Therapy Next, October/November 2019
Phase 1 dose-escalation clinical trial to determine the phase 2 dose of autologous TIL 1383I TCR gene-modified T cells using a retrovirus for…
Cover Story

Lumpers, Splitters, and the Move Toward New Taxonomy for Rheumatology

Healio Rheumatology, August 2019
Historians attribute Philip II of Macedon — father of Alexander the Great — as the source of the motto and political principle known as…
In the JournalsPerspective

New findings provide additional evidence of AFM, enterovirus link

August 14, 2019
Testing of 14 patients with acute flaccid myelitis, or AFM, showed they had antibodies against enteroviruses, especially EV-D68, in their…