Cleveland Clinic

This is your central portal for breaking news, the latest research and important updates from Cleveland Clinic. Bookmark this page and check back often for updates.

FDA News

FDA approves Keytruda-Inlyta combination for first-line treatment of advanced renal cell carcinoma

April 22, 2019
The FDA approved pembrolizumab in combination with axitinib for first-line treatment of advanced renal cell carcinoma. Pembrolizumab (Keytruda…
In the Journals

It’s not personal: Polyp detection better with higher volume, recent training

April 17, 2019
Residual confounding, and not an endoscopist’s personal characteristics like surgical specialty training or sex, may be responsible for…
At Issue

At Issue: Publication of CABANA results prompts further debate over AF ablation

April 12, 2019
When the results of the CABANA trial of atrial fibrillation ablation compared with medical therapy were presented at the Heart Rhythm Society Annual…
Meeting News

Escalated daunorubicin dose does not improve outcomes among older adults with acute myeloid leukemia

April 5, 2019
FORT WORTH, Texas — An escalated daunorubicin dose during induction chemotherapy did not improve clinical outcomes among older patients with…
Meeting News

Tips for disclosing medical errors

April 5, 2019
NATIONAL HARBOR, Md. — Disclosing medical errors can be incredibly challenging conversations, but when done the right way by presenting…
In the Journals

Comprehensive care may improve outcomes in STEMI

March 29, 2019
A comprehensive focus on STEMI care that includes transradial primary PCI, prompt guideline-directed medical therapy and door-to-balloon time…
Meeting News

New model accurately assesses VTE risk

March 26, 2019
NATIONAL HARBOR, Md. — A novel risk assessment model for venous thromboembolism accurately stratified risk among inpatients and demonstrated…

First-of-its-kind fellowship explores juncture of rheumatology, infectious disease

March 22, 2019
Leonard H. Calabrese, DO, chief medical editor of Healio Rheumatology and the director of the RJ Fasenmyer Center for Clinical Immunology at the…

Treatment Guidelines in Rheumatology: What Do You Hear When One Hand Claps?

Healio Rheumatology, March 2019
Leonard H. Calabrese, DO
We are privileged to have with us this month an esteemed panel of experts in the psoriatic arthritis space: M. Elaine Husni, MD, MPH, director of the…

What ACL graft is best for older active patients who are uncomfortable with receiving allograft tissue?

Orthopedics Today, March 2019
There is no question in my mind that the ideal ACL graft for an active older patient who is uncomfortable with an allograft is a quadrupled…
Orthopedics Today Grand Rounds

A man with ipsilateral genu valgum, meniscus deficiency and osteochondral lesion

Orthopedics Today, March 2019
Matthew L. Webb, MD; Atul F. Kamath, MD; James L. Carey, MD, MPH
A 21-year-old man presented with a 3-year history of intermittent 8/10 lateral right knee pain. He failed two prior surgical procedures done at…
In the Journals

Elevated CRP levels after ACS increase risk for cardiac events, death

March 6, 2019
Patients who had initial and sequential increases in high-sensitivity C-reactive protein levels 16 weeks after ACS had an increased risk for major…
Meeting News

Tivozanib shows PFS benefit over sorafenib for advanced kidney cancer

February 22, 2019
SAN FRANCISCO — Tivozanib induced higher 2-year PFS and objective response rates than sorafenib among patients with refractory metastatic renal…

Closing the Gap Between Patients and Rheumatology Providers: A New Problem?

Healio Rheumatology, February 2019
Leonard H. Calabrese, DO
In a recent article published in JAMA Network Open, Levy and colleagues surveyed more than 4,000 patients and queried them as to whether they had…
Meeting News

'Immunology boot camp' emphasizes role of chronic stress in autoimmune disease

February 15, 2019
SCOTTSDALE, Ariz. — Among the most important research in rheumatology over the past two decades has been the role of stress in the onset and…

Protein-targeting vaccine extends survival in glioblastoma

February 8, 2019
A vaccine that targets the protein survivin appeared safe and extended survival among patients with newly diagnosed glioblastoma, according to…
In the Journals PlusPerspective

Detection of JAK2 V617F mutations linked to myeloproliferative neoplasms

January 30, 2019
JAK2 V617F mutations detected by solid tumor sequencing appeared associated with coexistent myeloproliferative neoplasms, according to a…
The Take Home

The Take Home: VIVA

Cardiology Today's Intervention, January/February 2019
The annual VIVA conference, featuring a variety of hot topics in vascular intervention, was held from Nov. 5 to 8 in Las Vegas. Cardiology

Rheumatology and Burnout: Causes, Concerns and Hope

Healio Rheumatology, January 2019
Leonard H. Calabrese
The topic of burnout in medicine is certainly at the top of everyone’s list of critical issues. Consequently, we thought it timely that Healio
FDA News

FDA panel: Febuxostat benefits outweigh CV risks, but reduce use

January 14, 2019
A joint panel of the FDA’s Arthritis Advisory Committee and Drug Safety and Risk Management Advisory Committee voted 19-2 with one abstention…