Children’s Hospital of Philadelphia

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Spot the Rash

Blistering rash in a 1-year-old boy

Infectious Diseases in Children, February 2020
Michele Khurana, MD; Marissa J. Perman, MD
A 1-year-old boy presents with a diffuse rash on the body for the past 3 days (Figures 1 and 2). The rash started on his hands, then progressed to…
Cover Story

Shot in the Arm: Talking to Vaccine-hesitant Patients About Protecting Themselves

Healio Rheumatology, February 2020
As far as hot-button health care topics go, it is hard to top vaccines. Even dropped into a casual conversation, the idea itself — and this…
In the Journals

Peripherally inserted central catheters significantly increase blood clot, infection risks among children

January 28, 2020
Children with peripherally inserted central catheters demonstrated a significantly higher risk for venous thromboembolism, central line-associated…
Advanced Practice

CAR T-cell therapy for children: Meeting patient and family needs

HemOnc Today, January 25, 2020
Colleen Callahan, MSN, RN, CRNP; Amy Barry, MSN, RN, PPCNP-BC; Diane Baniewicz, MSN, RN, CRNP
Chimeric antigen receptor T-cell therapy is a promising immunotherapy for children with refractory or relapsed acute lymphoblastic leukemia who…

An emerging industry looks to take T cells to the cryobank

December 30, 2019
An increasing body of evidence shows that using younger, less heavily pretreated T cells results in more effective chimeric antigen receptor T-cell…
Spot the Rash

6-year-old girl presents with itchy rash on leg

Infectious Diseases in Children, December 2019
Michele Khurana, MD; Marissa J. Perman, MD
A 6-year-old girl presents with a rash on the back of her left leg for the past month. The rash is very itchy. She has a history of mild atopic…
In the Journals

Psoriasis risk spikes with anti-TNF use in children with inflammatory diseases

November 6, 2019
Children with either inflammatory bowel disease, chronic noninfectious osteomyelitis or juvenile idiopathic arthritis developed psoriasis at an…

Algorithm could help leverage data for pediatric oncology research

September 27, 2019
Investigators have developed an algorithm that appeared to accurately identify children with leukemia and lymphoma who would be appropriate for…
Trend Watch

Penn, Novartis end groundbreaking CAR-T relationship with new, more focused collaboration

September 16, 2019
The 7-year research and development alliance between Novartis and the University of Pennsylvania has concluded, with both organizations entering into…
In the Journals

Providers can help parents talk to teens about sex, alcohol use

September 10, 2019
Adolescents more frequently reported communicating with their parents about sex and alcohol use following an intervention in which pediatric primary…
In the Journals

AHA creates first scientific statement on Fontan circulation

August 5, 2019
As a greater number of patients who had Fontan operations reach adolescence and adulthood, more information on how to manage those patients is…

NCCN Releases Inaugural Pediatric ALL Clinical Practice Guidelines

Cell Therapy Next, July 2019
The National Comprehensive Cancer Network recently released its first clinical practice guidelines for children with acute lymphoblastic leukemia…
Meeting News

ASH announces award recipients

July 15, 2019
Several distinguished leaders in hematology will be honored with awards and special lectures at this year’s ASH Annual Meeting and Exposition…

Dana-Farber/Boston Children’s named nation’s best hospital for pediatric cancer

June 18, 2019
Dana-Farber/Boston Children’s Cancer and Blood Disorders Center has reclaimed its distinction as the No. 1 children’s hospital for cancer…

Boston Children’s tops U.S. News & World Report’s list for 6th year

June 18, 2019
Boston Children’s Hospital has been ranked the No. 1 children’s hospital for 2019-2020 by U.S. News & World Report. This marks the…
Spot the Rash

11-year-old female presents with worsening facial rash

Infectious Diseases in Children, June 2019
Colleen H. Cotton, MD; Marissa J. Perman, MD
An 11-year-old healthy female presented to the dermatology clinic for evaluation of a facial rash that had lasted for 3 weeks. Initially, it was a…
FDA News

Device to close atrial septal defects approved by FDA

June 4, 2019
W.L. Gore and Associates announced its occluder device was approved by the FDA for percutaneous closure of ostium secundum atrial septal defects. The…

Proton therapy shows efficacy with low toxicity in pediatric high-risk neuroblastoma

May 13, 2019
Children with high-risk neuroblastoma derived excellent outcomes from proton radiation therapy with minimal toxicity, according to results of the…
Meeting News

Outpatient CAR T-cell therapy possible if done earlier

May 13, 2019
PHILADELPHIA — Chimeric androgen receptor T-cell therapy has a reputation as a game-changing therapy with a hefty price tag. However, as CAR…

Experts applaud $500 million proposal for pediatric cancer research, but say more needed

April 8, 2019
President Donald J. Trump recognized pediatric cancer research as a national health priority during his State of the Union address in February, when…