Children’s Hospital of Philadelphia

This is your central portal for breaking news, the latest research and important updates from Children’s Hospital of Philadelphia. Bookmark this page and check back often for updates.


An emerging industry looks to take T cells to the cryobank

December 30, 2019
An increasing body of evidence shows that using younger, less heavily pretreated T cells results in more effective chimeric antigen receptor T-cell…
Spot the Rash

6-year-old girl presents with itchy rash on leg

Infectious Diseases in Children, December 2019
Michele Khurana, MD; Marissa J. Perman, MD
A 6-year-old girl presents with a rash on the back of her left leg for the past month. The rash is very itchy. She has a history of mild atopic…
In the Journals

Psoriasis risk spikes with anti-TNF use in children with inflammatory diseases

November 6, 2019
Children with either inflammatory bowel disease, chronic noninfectious osteomyelitis or juvenile idiopathic arthritis developed psoriasis at an…

Algorithm could help leverage data for pediatric oncology research

September 27, 2019
Investigators have developed an algorithm that appeared to accurately identify children with leukemia and lymphoma who would be appropriate for…
Trend Watch

Penn, Novartis end groundbreaking CAR-T relationship with new, more focused collaboration

September 16, 2019
The 7-year research and development alliance between Novartis and the University of Pennsylvania has concluded, with both organizations entering into…
In the Journals

Providers can help parents talk to teens about sex, alcohol use

September 10, 2019
Adolescents more frequently reported communicating with their parents about sex and alcohol use following an intervention in which pediatric primary…
In the Journals

AHA creates first scientific statement on Fontan circulation

August 5, 2019
As a greater number of patients who had Fontan operations reach adolescence and adulthood, more information on how to manage those patients is…

NCCN Releases Inaugural Pediatric ALL Clinical Practice Guidelines

Cell Therapy Next, July 2019
The National Comprehensive Cancer Network recently released its first clinical practice guidelines for children with acute lymphoblastic leukemia…
Meeting News

ASH announces award recipients

July 15, 2019
Several distinguished leaders in hematology will be honored with awards and special lectures at this year’s ASH Annual Meeting and Exposition…

Dana-Farber/Boston Children’s named nation’s best hospital for pediatric cancer

June 18, 2019
Dana-Farber/Boston Children’s Cancer and Blood Disorders Center has reclaimed its distinction as the No. 1 children’s hospital for cancer…

Boston Children’s tops U.S. News & World Report’s list for 6th year

June 18, 2019
Boston Children’s Hospital has been ranked the No. 1 children’s hospital for 2019-2020 by U.S. News & World Report. This marks the…
Spot the Rash

11-year-old female presents with worsening facial rash

Infectious Diseases in Children, June 2019
Colleen H. Cotton, MD; Marissa J. Perman, MD
An 11-year-old healthy female presented to the dermatology clinic for evaluation of a facial rash that had lasted for 3 weeks. Initially, it was a…
FDA News

Device to close atrial septal defects approved by FDA

June 4, 2019
W.L. Gore and Associates announced its occluder device was approved by the FDA for percutaneous closure of ostium secundum atrial septal defects. The…

Proton therapy shows efficacy with low toxicity in pediatric high-risk neuroblastoma

May 13, 2019
Children with high-risk neuroblastoma derived excellent outcomes from proton radiation therapy with minimal toxicity, according to results of the…
Meeting News

Outpatient CAR T-cell therapy possible if done earlier

May 13, 2019
PHILADELPHIA — Chimeric androgen receptor T-cell therapy has a reputation as a game-changing therapy with a hefty price tag. However, as CAR…

Experts applaud $500 million proposal for pediatric cancer research, but say more needed

April 8, 2019
President Donald J. Trump recognized pediatric cancer research as a national health priority during his State of the Union address in February, when…
Meeting News

Pharmacists play key role in guiding adolescents, young adults through cancer survivorship

April 3, 2019
FORT WORTH, Texas — Adolescent and young adult cancer survivors are more likely than their peers to develop chronic health conditions, and…
Cover Story

New indications may accelerate ‘explosion’ in CAR T-cell therapy, but more education still needed

HemOnc Today, March 25, 2019
Years of research into chimeric antigen receptor T-cell therapy for cancer treatment is finally paying dividends. When Renier J. Brentjens, MD

Should pediatric cancer survivors previously exposed to neck irradiation undergo ultrasound screening for thyroid cancer?

HemOnc Today, March 10, 2019
POINT We have very limited data on whether active surveillance of patients treated with radiation therapy for a nonthyroid head and neck cancer is…
Cover Story

‘There needs to be urgency’ to address late endocrinopathies in childhood cancer survivors

HemOnc Today, March 10, 2019
For pediatric cancer survivors, the disease and its treatments place them at risk for subsequent health complications, many of which are endocrine…