Children’s Hospital of Philadelphia

This is your central portal for breaking news, the latest research and important updates from Children’s Hospital of Philadelphia. Bookmark this page and check back often for updates.

Meeting News

Omalizumab improves asthma outcomes despite inconsistent adherence

October 30, 2017
BOSTON — Even if children are not fully adherent to treatment, those receiving omalizumab for the management of asthma have a significantly…
In the Journals

Preterm delivery traits predict early-onset sepsis risk

October 24, 2017
Delivery characteristics of preterm infants born at 22 to 28 weeks’ gestational age, such as preterm onset labor and preterm amniotic membrane
Cover Story

Guideline adherence required to address constipation concerns

Infectious Diseases in Children, October 2017
Pediatric constipation is one of the most frequently treated chronic conditions worldwide, according to a review by Nurko and colleagues in the…
In the Journals PlusPerspective

Crizotinib effectively targets ALK pathway in pediatric cancers

October 9, 2017
Crizotinib induced robust and sustained clinical responses in children with relapsed anaplastic large cell lymphoma and metastatic or unresectable…
In the Journals

Families of children treated with ECMO report certain favorable outcomes

October 9, 2017
Family-reported outcomes of pediatric cardiac patients once supported by extracorporeal membrane oxygenation, or ECMO, were encouraging, according to…
Cover StoryPerspective

CAR T-cell therapy approval huge step for oncology, but only ‘beginning of story’

HemOnc Today, September 25, 2017
The FDA’s approval of tisagenlecleucel for the treatment of children and young adults with relapsed or refractory B-cell acute lymphoblastic…
Round Tables

Surgical hip dislocation in children is safe for muscles, preserves blood supply

Orthopedics Today, September 2017
This Orthopedics Today Round Table features surgical hip dislocation in children, a procedure described by Reinhold Ganz, MD, about 17 years ago…
Cover Story

Advancing Standards of Care in Pediatric Rheumatology

Healio Rheumatology, August 2017
The most important challenge facing pediatric rheumatology is a lack of pediatric rheumatologists, according to many experts in the field. The…

Kids First Data Resource Center set to ‘unlock potential’ of genomic data in pediatric cancer

August 16, 2017
The NIH established the Kids First Data Resource Center, a pediatric cancer and rare disease data program that will enable clinicians and researchers…
Spot the Rash

A 13-year-old boy with a worsening neck, arm rash

Infectious Diseases in Children, August 2017
Marissa J. Perman, MD; Scarlett Boulos, MD
A 13-year-old boy presented with a 10-day history of a rash that started on his left arm after receiving his influenza vaccine. Following…

NCI, Children’s Oncology Group collaborate on trial to evaluate targeted drugs for pediatric cancers

July 24, 2017
NCI and the Children’s Oncology Group today announced enrollment opened for a phase 2 study designed to evaluate targeted therapies in children…

Boston Children’s, CHOP ranked best hospitals for pediatric GI, GI surgery

June 27, 2017
Boston Children’s Hospital, Children’s Hospital of Philadelphia and Cincinnati Children’s Hospital Medical Center ranked as the top…

Boston Children’s Hospital named best pediatric hospital by U.S. News & World Report

June 27, 2017
Boston Children’s Hospital has been ranked the No. 1 pediatric hospital in the nation for the fourth consecutive year, according to the…
Meeting NewsVideo

VIDEO: Pembrolizumab may improve response to CAR T-cell therapy in children with ALL

June 20, 2017
CHICAGO — The combination of pembrolizumab and CAR T-cell therapy appeared safe and effective in a subset of patients with acute lymphoblastic…
Spot the Rash

A 12-year-old girl with scattered erythematous papules, pustules on her neck

Infectious Diseases in Children, June 2017
Marissa J Perman, MD; Scarlett Boulos, MD
A 12-year-old girl presented with a 3-week history of an itchy rash on the back of her neck. She was previously treated twice with permethrin 1%…

Consistent advocacy needed to thwart resurgence: Measles over 3 decades

Infectious Diseases in Children, June 2017
Between 1987 and 1988, the number of measles cases reported to the CDC decreased by 7%, from 3,652 cases in 1987 to 3,411 in 1988. However, in 1989…
Meeting NewsPerspective

CAR T-cell immunotherapy prompts durable response for ALL

June 4, 2017
CHICAGO — Young patients with extramedullary relapse of acute lymphoblastic leukemia achieved potent and durable responses to single-agent…
In the Journals

One-third of teens with autism acquire driver's license, closely following eligibility

May 17, 2017
Although only one-third of teenagers with autism spectrum disorder acquire an intermediate driver’s license, 90% of those who did acquired…

Children’s Hospital of Philadelphia appoints section chief

May 17, 2017
Stephan A. Grupp , MD, PhD, has been named chief of the section of cellular therapy and transplant within the division of oncology at…
Cover Story

Clinicians push back against vaccine myths

Infectious Disease News, May 2017
Despite the body of literature supporting their use, vaccines are still not fully accepted by the public, which increases the risk for outbreaks of…