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This is your central portal for breaking news, the latest research and important updates from Brigham and Women’s Hospital. Bookmark this page and check back often for updates.

Dextromethorphan-quinidine: What PCPs need to know

January 18, 2019
The FDA approved combined dextromethorphan hydrobromide and quinidine sulfate for the treatment of pseudobulbar affect, a condition characterized by…
In the Journals

At-home hypertension program may control BP in 7 weeks

January 18, 2019
Most patients who were treated for hypertension by a home-based BP control program that was run by nonphysicians achieved BP control in an average of…
In the Journals

Spironolactone effective as HFpEF treatment regardless of kidney function, but safety less clear

January 17, 2019
The efficacy of spironolactone in patients with HF with preserved ejection fraction was consistent across the range of kidney function, although…
In the Journals

Genetic factor may identify patients at risk for spontaneous coronary artery dissection

January 17, 2019
The first genetic risk locus for spontaneous coronary artery dissection has been identified, according to a study published in the Journal of the
In the Journals

Medicaid expansion fails to affect acute MI outcomes

January 16, 2019
Among low-income patients with acute MI, residing in a state with Medicaid expansion had no effect on quality of care or outcomes, according to new…
In the Journals

Less than 6 hours of sleep per night increases atherosclerosis risk

January 14, 2019
Elevated risk for subclinical multiterritory atherosclerosis occurred in patients with short sleep time or fragmented sleeping, according to findings…
In the Journals

Aspiration thrombectomy use declined over time with small excess risk

January 11, 2019
The use of aspiration thrombectomy during primary PCI in patients with STEMI declined by more than 50% since 2011, and since then, there was small…
In the Journals

Canagliflozin not associated with fracture risk

January 4, 2019
Research published in Annals of Internal Medicine indicated no increased risk for fracture with the use of canagliflozin among patients with…
In the Journals Plus

Radiation, androgen deprivation therapy after prostatectomy may improve survival in aggressive prostate cancer

January 3, 2019
External beam radiotherapy and androgen deprivation therapy after radical prostatectomy may reduce mortality risk among men with high-risk prostate…

Cardiology Today’s Editorial Board discusses top news of 2018

December 29, 2018
There were many noteworthy developments in cardiology in 2018. A number of trials were published that changed practice, and important new guidelines…
In the Journals

Untreated sleep apnea may increase odds of hypertension in black adults

December 26, 2018
Untreated moderate or severe obstructive sleep apnea is related to increased odds of resistant hypertension and inadequate BP control in black…
In the Journals

Evolocumab response rate high in FOURIER population

December 26, 2018
Most patients assigned the PCSK9 inhibitor evolocumab in the FOURIER CV outcomes trial responded to it, researchers reported in JAMA Cardiology
In the Journals

Increase in post-discharge mortality in heart failure, pneumonia follows readmission reduction program

December 21, 2018
Implementation of the Hospital Readmissions Reduction Program was followed by an increase in 30-day post-discharge mortality for patients…
In the Journals

3D printing may be used for fit-testing valves before TAVR

December 20, 2018
Researchers developed a novel workflow using 3D printing to help clinicians determine what valve size to use before performing transcatheter aortic…
In the Journals

Inappropriate PCIs decrease as practices shift

December 19, 2018
Declines in inappropriate PCIs may be associated with shifts in coding and/or diagnostic practices, according to a study published in JAMA Internal
In the Journals

Opioid use doubled in patients with RA from 2002 to 2015

December 19, 2018
Persistent opioid use among patients with rheumatoid arthritis doubled from 2002 to 2015, with pain and antidepressant treatment being the strongest…
In the Journals

First-trimester use of ondansetron not linked to infant cardiac malformation

December 18, 2018
The use of ondansetron, a 5-HT3 receptor antagonist prescribed for nausea and vomiting during pregnancy, was not associated with congenital or…
Cover Story

Medical optimization readies patients for successful orthopedic surgery

Orthopedics Today, December 2018
Preoperative medical optimization of patients is an approach orthopedic surgeons can use to reduce postoperative complications and improve the…
Meeting NewsPerspective

Surgery choice affects quality of life among younger patients with breast cancer

December 7, 2018
SAN ANTONIO — Local therapy decisions appeared to significantly affect quality of life among young breast cancer survivors, according to study…
In the Journals

Mortality rates, patient satisfaction better at top-ranked cardiology hospitals

November 28, 2018
Thirty-day mortality rates were lower and patient satisfaction was higher at the nation’s top-ranked hospitals for cardiology and heart surgery…