10 stories for the 10th annual World Sepsis Day
Monday marks the 10th annual World Sepsis Day, an initiative established in 2012 by the nonprofit Global Sepsis Alliance to raise awareness of sepsis, which kills at least 11 million people each year worldwide.
According to the CDC, one out of every three patients who dies in a hospital in the United States has sepsis. The condition affects at least 1.7 million American adults each year, killing nearly 270,000, yet many people are unaware of it.
Healio compiled a list of 10 stories to mark the 10th anniversary of World Sepsis Day, which is held each year on Sept. 13.
Early ID consultation reduces risk for death in patients with sepsis
Receiving an infectious disease consultation within 12 hours of arriving at the hospital was associated with a 40% reduced risk for in-hospital mortality among patients with sepsis, according to study findings. Read more.
Nearly 25% of maternal deaths in US are sepsis related
According to research published in JAMA, nearly one-quarter of all maternal deaths in the United States from 2013 to 2016 were related to sepsis, and more than a third of those deaths occurred after hospital discharge. Read more.
Sepsis surpasses pneumonia as most common hospital infection in SLE
Sepsis surpassed pneumonia as the most common hospitalized infection in systemic lupus erythematosus, with a rate that increased more than sixfold from 1998-2000 to 2015-2016, according to data published in Arthritis & Rheumatology. Read more.
Steroid bursts in children linked to GI bleeding, sepsis, pneumonia
Oral corticosteroid bursts were associated with a 1.4- to 2.2-fold increased risk for gastrointestinal bleeding, sepsis and pneumonia among children within the first month after use, according to study results published in JAMA Pediatrics. Read more.
Companies collaborate on technology to improve sepsis care
Ontera and QuantuMDx announced that they will collaborate on a technology to quickly detect bloodstream infections and drug resistance, with an aim toward improving outcomes for patients with sepsis. Read more.
Study finds high rate of morbidity, mortality associated with native shoulder joint sepsis
Multiple underlying risk factors — such as IV drug use — and increased mortality rates were found in patients with native shoulder joint sepsis who are treated with surgical irrigation and debridement, according to study findings. Read more.
Obtain blood culture before initiating antimicrobial therapy in sepsis
Among patients with severe manifestations of sepsis, the sensitivity of blood cultures decreased after initiation of empirical antimicrobial therapy, according to a study published in the Annals of Internal Medicine. Read more.
Neonatal early-onset sepsis calculator reduces use of empirical antibiotics
Use of a clinical risk stratification tool called the neonatal early-onset sepsis calculator was associated with a substantial reduction in the use of empirical antibiotics for the condition, according to findings from a systematic review and meta-analysis published in JAMA Pediatrics. Read more.
New biomarker may identify septic patients at higher risk for mortality
Researchers identified a protein, oncostatin-M, as a potential prognostic biomarker and therapeutic target for sepsis, according to a study published in The Journal of Infectious Diseases. Read more.
BARDA, Cytovale launch study to diagnose sepsis in patients with COVID-19
Cytovale announced that it would expand its partnership with the Biomedical Advanced Research and Development Authority to examine the use of Cytovale’s Rapid Sepsis Diagnostic System for diagnosing sepsis in patients with potential respiratory infections, including COVID-19. Read more.
CDC. Sepsis. https://www.cdc.gov/sepsis/index.html. Accessed September 13, 2021.
World Sepsis Alliance. About World Sepsis Day. https://www.worldsepsisday.org/about. Accessed September 13, 2021.