Issue: February 2013
Source: Jemal A. J Natl Cancer Inst. 2013;doi:10.1093/jnci/djs491.
January 07, 2013
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Rates of two HPV-related cancers increased, HPV vaccination low

Issue: February 2013
Source: Jemal A. J Natl Cancer Inst. 2013;doi:10.1093/jnci/djs491.
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There have been increased incidence rates for some HPV-related cancers and low HPV vaccination among adolescents, according to findings in the Annual Report to the Nation on the Status of Cancer.

The report is a collaboration among the American Cancer Society, the CDC, the National Cancer Institute and the North American Association of Central Cancer Registries.

Overall, death rates for all cancers have declined. The incidence of cervical cancer decreased for women in all racial and ethnic groups, except for American Indian/Alaska Native. However, the incidence rates for oropharyngeal cancer and anal cancer, both associated with HPV, have increased. The increase was larger among those aged 55 to 64 years.

HPV-associated cancers were responsible for 3.3% of cancers among women and 2% of cancers among men. For women, cervical cancers comprised 53.4% of HPV-related cancers and oropharyngeal cancer accounted for 11.6%. For men, oropharyngeal cancers comprised 78.2% of the HPV-related cancers.

Among girls aged 13 to 17 years, 48.7% received one or more doses of the HPV vaccine. Only 32% of girls received all three doses. Idaho has the lowest coverage, with 17.6% of girls receiving three doses, and Rhode Island had the highest coverage, with 55.1% receiving three doses. Three-dose coverage was lower in Southern states and among the uninsured.

Among women aged 21 to 65 years, 86.7% had a Pap test within the previous 3 years. Pap testing was lowest in the areas with the lowest HPV vaccination rates, where the incidence of cervical cancer was also the highest.

“A greater understanding of the increasing incidence rates for HPV-associated cancers requires continued monitoring of changes in sexual practices that increase HPV exposure as well as of trends in the population-based prevalence of HPV infections at anatomic sites where these cancers arise,” the researchers wrote.

Disclosure: The researchers report no relevant financial disclosures.