In the Journals

Ziv-aflibercept plus FOLFIRI extended OS in metastatic colorectal cancer

Ruff P. Eur J Cancer. 2014;doi:10.1016/j.ejca.2014.10.019.
The addition of ziv-aflibercept to FOLFIRI chemotherapy was associated with durable improvements in survival among patients with metastatic…
In the Journals

HIV evolution bypassed immune resistance, but reduced virulence

Payne R. PNAS. 2014;doi:10.1073/pnas.1413339111.
HIV strains that evolve to bypass human immune responses may do so at the cost of a reduced ability to replicate, according to recent study …
In the Journals

Lobectomy superior to sublobar resection for elderly patients with early-stage NSCLC

Shirvani SM. JAMA Surg. 2014; doi:10.1001/jamasurg.2014.556.
Lobectomy conferred better outcomes than sublobar resection in elderly patients with early-stage non-small cell lung cancer, according to results of…
In the Journals

Novel method quickly identifies bacteria, resistance with accuracy

Mezger A. J Clin Microbiol. 2014;doi:10.1128/JCM.02434-14.
A new method of rapidly identifying bacteria also may be able to accurately determine their antibiotic resistance and sensitivity, according to…
In the JournalsPerspective

Early valve surgery did not affect mortality in S. aureus endocarditis

Chirouze C. Clin Infect Dis. 2014;doi:10.1093/cid/ciu871.
Early valve surgery did not reduce 1-year mortality among patients with Staphylococcus aureus prosthetic valve infective endocarditis, according to…
In the Journals

SLNB did not improve survival in head and neck melanoma

Sperry SM. JAMA Otolaryngol Head Neck Surg. 2014;doi:10.1001/jamaoto.2014.2530.
Patients with head and neck melanoma who underwent sentinel lymph node biopsy derived no disease-specific survival benefit compared with patients who…
In the Journals

Telephone counseling increased cardiomyopathy screenings in childhood cancer survivors

December 4, 2014
The addition of telephone counseling to a printed survivorship care plan increased the frequency with which survivors of childhood cancer at risk for…
In the Journals

Crizotinib superior to chemotherapy in advanced, ALK-positive NSCLC

Solomon BJ. N Engl J Med. 2014;371:2167-2177.
Patients with advanced, ALK-positive non–small cell lung cancer who received first-line treatment with crizotinib demonstrated improved outcomes…
In the Journals

Deferring ART more than 1 year reduced chance of immune recovery

Okulicz J. JAMA Intern Med. 2014;doi:10.1001/jamainternmed.2014.4010.
Deferring antiretroviral therapy more than 12 months after the estimated date of seroconversion reduced the possibility of restoring the immune…
In the Journals

MERS spread linked to failures in infection control

Maltezou HC. Am J Infect Control. 2014;42:1261-1265.
Gaps in infection control were largely responsible in numerous published incidents of health care-associated transmission of Middle East…
In the Journals

High-dose chemotherapy failed to extend PFS in germ cell tumors

Necchi A. Ann Oncol. 2014;doi:10.1093/annonc/mdu485.
Patients with advanced germ cell tumors who received cisplatin, etoposide and bleomycin chemotherapy demonstrated comparable PFS as those who…
In the Journals

ExoU+ genotype linked to early mortality in P. aeruginosa patients

Peña C. Clin Infect Dis. 2014;doi:10.1093/cid/ciu866.
A positive correlation existed between the exoU+ genotype and increased risk for early mortality in patients with P. aeruginosa bloodstream…
In the Journals

Women with breast cancer demonstrate elevated long-term risk for depression

Suppli NP. J Clin Oncol. 2014;doi:10.1200/JCO.2013.54.0419.
Women with breast cancer demonstrate increased risk for depression several years after diagnosis, according to study results. Nis P. Suppli
In the Journals

Several carcinogenic biomarker levels elevated in cigar smokers

Chen J. Cancer Epidemiol Biomarkers Prev. 2014;doi:10.1158/1055-9965.EPI-14-0849.
Cigar smoking is linked to higher levels of carcinogenic tobacco exposure biomarkers and may be as harmful as cigarette smoking, according to study…
In the Journals

High radioactive iodine-131 exposure dose linked to aggressive thyroid cancer

December 2, 2014
Children and adolescents exposed to high doses of radioactive iodine-131 after the Chernobyl nuclear power plant accident experienced greater rates…
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