In the Journals

E-cigarettes unhelpful for smoking cessation among patients with cancer

Borderud SP. Cancer. 2014;doi:10.1002/cncr.28811.
A study of patients with cancer who smoke showed those who used electronic cigarettes were more nicotine-dependent than nonusers. Those who used…
In the Journals

Increase in skirt size led to higher risk for postmenopausal breast cancer

Fourkala E. BMJ Open. 2014;doi:10.1136/bmjopen-2014-005400.
An increase in skirt size each decade among women aged between their mid-20s and mid-50s appeared to be associated with a 33% elevated risk for…
In the Journals

Statin use after colorectal cancer diagnosis improved survival

Cardwell CR. J Clin Oncol. 2014;doi:10.1200/JCO.2013.54.4569.
Patients with colorectal cancer who used statins after diagnosis demonstrated improved survival outcomes compared with those who did not use statins…
In the JournalsPerspective

Modified gene therapy shows promise in SCID-X1

Hacein-Bey-Abina S. New Engl J Med. 2014;371:1407-11417.
A majority of boys with X-linked severe combined immunodeficiency experienced T-cell recovery and infection clearance after undergoing gene therapy…
In the Journals

Eclampsia, acute systemic infection increased risk for postpartum VTE

Sultan AA. Blood. 2014;doi:10.1182/blood-2014-05-572834.
Women with preeclampsia/eclampsia and postpartum acute systemic infection experienced the greatest risk for developing venous thromboembolism during…
In the Journals

Preoperative ultrasound imaging of thyroid cancer essential to preventing additional surgeries

Yeh MW. Thyroid. 2014;doi:10.1089/thy.2014.0096.
The use of comprehensive preoperative imaging enables complete initial surgical removal of thyroid cancer and associated metastases from cervical…
In the Journals

Low levels of influenza documented in US through summer

Blanton L. MMWR. 2014;63:861-864.
Influenza A(H1N1)pdm09, influenza A(H3N2) and influenza B viruses circulated worldwide from May 18 to Sept. 20, but the United States experienced low…
In the JournalsPerspective

Radical cystectomy, urinary diversion increased fracture risk among patients with bladder cancer

Gupta A. J Clin Oncol. 2014;doi:10.1200/JCO.2013.54.3173.
Patients with bladder cancer who underwent radical cystectomy and urinary diversion demonstrated an increased risk for bone fracture, according to…
In the JournalsPerspective

Two novel mutations linked to ALK inhibitor resistance in NSCLC

October 7, 2014
Two novel ALK mutations, V1180L and I1171T, were associated with resistance to crizotinib and alectinib but were sensitive to other next-generation…
In the Journals

More evidence may be needed to confirm long-term HPV vaccine efficacy

Deleré Y. Dtsch Arztebl Int. 2014;111:584-591.
Study data from long-term observation did not indicate any loss of antiviral protection after vaccination against HPV types 16 and 18, but stronger…
In the Journals

Platinum-based chemotherapy extended OS in BRCA-associated pancreatic ductal adenocarcinoma

Golan T. British J Cancer. 2014;doi:10.1038/bjc.2014.418.
Patients with advanced BRCA-associated pancreatic ductal adenocarcinoma treated with platinum-based chemotherapy experienced longer OS than those…
In the Journals

One-third of cancer patients experienced anxiety, mental health disorders

Mehnert A. J Clin Oncol. 2014; doi:10.1200/JCO.2014.56.0086.
About one in three patients with cancer experienced some level of clinically relevant mental health challenge, such as anxiety, depressive disorders…
In the Journals

Beta-lactam monotherapy failed to show noninferiority for CAP

Garin N. JAMA Intern Med. 2014;doi:10.1001/jamainternmed.2014.4887.
Researchers were unable to demonstrate noninferiority of beta-lactam monotherapy compared with beta-lactam/macrolide combination therapy for…
In the Journals

Typhoid surveillance, vaccination lacking in endemic areas

Date K. MMWR. 2014;63:855-860.
Among the 48 countries in the WHO Southeast Asia and Western Pacific regions, only nine reported implementing typhoid vaccination programs and 23…
In the Journals

Low vaccination rates, comorbidities risk factors for pH1N1-related pneumonia

Gomez AG. Emerg Infect Dis. 2014;doi:10.3201/eid2009.140115.
Low vaccination coverage and comorbidities such as diabetes and obesity appeared to be significant risk factors for influenza-related pneumonia in…
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