In the Journals Plus

HbA1c promising as predictive measure for cystic fibrosis-related diabetes

Choudhury M, et al. Diabet Med. 2019;doi:10.1111/dme.13912.
Adults with cystic fibrosis and HbA1c levels of 37 mmol/mol or more are at greater risk for dysglycemia and cystic fibrosis-related diabetes than…
In the Journals Plus

Analysis shows ‘meaningful’ decline in outpatient antibiotics in New England

Cocoros NM, et al. Infect Control Hosp Epidemiol. 2019;doi:10.1017/ice.2018.341.
An examination of outpatient antibiotics dispensed within a single commercial health insurance plan in New England showed a “meaningful”…
In the Journals Plus

Insulin dosing system associated with 1% HbA1c reduction in type 2 diabetes

Bergenstal RM, et al Lancet. 2019;doi:10.1016/s0140-6736(19)30368-x.
Evans ML, et al. Lancet. 2019;doi:10.1016/s0140-6736(19)30416-7.
Adults with type 2 diabetes prescribed insulin therapy who were assigned to an automated dosing support system for 6 months saw an average 1%…
In the Journals Plus

HIV status does not preclude receipt of curative cervical cancer therapy in Botswana

Grover S, et al. Cancer. 2019;doi:10.1002/cncr.31972.
Little RF. Cancer. 2019;doi:10.1002/cncr.31974.
Women in Botswana with well-managed HIV had the same access to curative chemoradiotherapy for cervical cancer as women without HIV, according to…
In the Journals Plus

Maternal cortisol to cortisone ratio may predict preeclampsia, fetal growth restriction

Jayasuriya NA, et al. J Clin Endocrinol Metab. 2019;doi:10.1210/jc.2018-02312.
A lower maternal serum cortisol to cortisone ratio, a marker of placental function, precedes the clinical manifestation of preeclampsia and preterm…
In the Journals Plus

Mismatch repair deficiency linked to increased risk for endometrial cancer recurrence

Backes FJ, et al. Cancer. 2018;doi:10.1002/cncr.31901.
Eskander RN. Cancer. 2018; doi:10.1002/cncr.31902.
Women with high-intermediate-risk endometrioid endometrial cancer and defective DNA mismatch repair had higher recurrence rates and poorer RFS than…
In the Journals

Spray bleach significantly reduces C. difficile spores in non-CDI rooms

Wong, YKN, et al. Am J Infect Control. 2019;doi:10.1016/j.ajic.2018.12.023.
A recent study found that using a spray bleach for post-discharge cleaning significantly reduced the recovery of Clostridioides
In the Journals Plus

Apixaban superior to rivaroxaban in preventing recurrent venous thromboembolism, major bleeding

Dawwas G, et al. Lancet Haematol. 2018;doi:10.1016/S2352-3026(18)30191-1.
Frere C and Farge D. Lancet Haematol. 2018;doi:10.1016/S2352-3026(18)30211-4.
Apixaban appeared more effective than rivaroxaban in preventing recurrent venous thromboembolism without major bleeding events, according to results…
In the Journals Plus

Better knowledge of gadolinium retention risks needed for pituitary tumor MRIs

Nachtigall LB, et al. Pituitary. 2019;doi:10.1007/s11102-018-0924-0.
Pituitary tumor management via ongoing MRIs is recommended by most endocrinologists and pituitary neurosurgeons, but there is a need to improve…
In the Journals Plus

Vaginal TFV gel may protect against HSV-2 in women

Marrazzo JM, et al. J Infect Dis. 2019;doi:10.1093/infdis/jiz045.
After controlling for sexual behavior and HIV-1 acquisition, adherence to vaginal tenofovir gel was associated with a trend toward reduced risk for…
In the Journals Plus

Marker of inflammation associated with depression in patients with lung cancer

McFarland, D et al. Cancer. 2018;doi:10.1002/cncr.31859
Elevated C-reactive protein, a marker of systemic inflammation, appeared associated with depression among patients with metastatic lung cancer…
In the Journals PlusPerspective

Carbs before sprinting exercises do not disrupt glycemic management

Soon WHK, et al. Diabet Med. 2019;doi:10.1111/dme.13914.
Glycemic management for young people with type 1 diabetes may not be negatively affected by carbohydrate intake before exercise that includes…
In the Journals Plus

Direct oral anticoagulants safe, effective in patients with VTE and thrombophilia

Elsebaie MA, et al. J Thromb Haemost. 2019;doi:10.1111/jth.14398.
Patients with thrombophilia had low rates of venous thromboembolism recurrence and bleeding events after treatment with direct oral anticoagulants…
In the Journals Plus

HIV infection linked to shorter survival in hepatocellular carcinoma

Pinato D, et al. J Clin Oncol. 2018;doi:10.1200/JCO.18.00885.
HIV seropositivity appeared associated with shorter OS among patients with hepatocellular carcinoma despite sufficient antiretroviral treatment…
In the Journals Plus

Metformin may reduce risk for miscarriage, preterm birth in pregnancy with PCOS

Løvvik TS, et al. Lancet Diabetes Endocrinol. 2019;doi:10.1016/s2213-8587(19)30002-6.
Pregnant women with polycystic ovary syndrome assigned to metformin therapy for the duration of pregnancy were less likely to experience a late-term…
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