In the Journals Plus

High numbers of HIV-positive MSM not being tested for syphilis

de Voux A, et al. Clin Infect Dis. 2018;doi:10.10.1093/cid/ciy571.
Nearly one-third of sexually active HIV-positive men who have sex with men are not tested for syphilis at least annually, researchers reported in a…
In the Journals Plus

Among ESBL-producing organisms, K. pneumoniae may be deadlier than E. coli

Burnham JP, et al. Infect Control Hosp Epidemiol. 2018;doi:10.1017/ice.2018.142.
Scheuerman O, et al. Infect Control Hosp Epidemiol. 2018;doi:10.1017/ice.2018.63.
In a retrospective evaluation of patients at a St. Louis hospital, extended-spectrum beta-lactamase-producing — or ESBL-producing —…
In the Journals Plus

MGMT promoter methylation prognostic biomarker for low-grade glioma

Bell EH, et al. JAMA Oncol. 2018;doi:10.1001/jamaoncol.2018.1977.
O6-methylgaunine-DNA-methyltransferase, or MGMT, promoter methylation appeared to be significantly associated with PFS and OS among patients with…
In the Journals Plus

Emergency colon cancer surgery conducted over weekend has poorer outcomes

Huijts DD, et al. J Natl Compr Canc Netw. 2018;doi:10.6004/jnccn.2018.7016.
Patients who underwent weekend emergency surgery for colon cancer appeared to have greater mortality and more severe complication rates than patients…
In the Journals Plus

Population-level decreases in alcohol, tobacco use could reduce cancer mortality

Jiang H, et al. JAMA Network Open. 2018;doi:10.1001/jamanetworkopen.2018.0713.
Population-level reductions in tobacco and alcohol consumption could lower cancer mortality, according to findings from a population-based cohort
In the Journals Plus

For transgender youths, delay in cross-sex HT initiation increases risk for smoking

Menino DD, et al. Transgend Health. 2018;doi:10.1089/trgh.2018.0002.
Among transgender adolescents, a longer delay between the recognition of transgender identity and the initiation of cross-sex hormone therapy is…
In the Journals Plus

Citizen scientists discover disease-carrying ticks in 83 new US counties

Nieto NC, et al. PLoS One. 2018;doi:10.1371/journal.pone.0199644.
Researchers discovered that ticks capable of carrying Lyme and other tick-borne diseases were found in 83 counties where they had previously never
In the Journals Plus

TB vaccines ineffective against initial infection

Nemes E, et al. N Engl J Med. 2018;doi:10.1056/NEJMoa1714021.
In a recent phase 2 trial, an investigational tuberculosis vaccine, H4:IC31, and the bacille Calmette-Guérin, or BCG, vaccine both lacked efficacy…
In the Journals Plus

Substantial variation exists in surgeon acceptance of more limited breast cancer surgery

Morrow M, et al. JAMA Oncol. 2018;doi:10.1001/jamaoncol.2018.1908.
Javid SH and Anderson BO. JAMA Oncol. 2018;doi:10.1001/jamaoncol.2018.1939.
Surgeon acceptance of findings recommending against axillary lymph node dissection for breast cancer varied widely and appeared more common among…
In the Journals Plus

Pancreatic adenocarcinoma mortality risk outweighed by other causes after 9 years

Swords DS, et al. JAMA Oncol. 2018;doi:10.1001/jamaoncol.2018.2442.
Patients who survived 8.75 years after being diagnosed with pancreatic adenocarcinoma were more likely to die of other causes than of their cancer…
In the Journals Plus

Fasting glucose plus physical performance may predict diabetes risk

Zhang W, et al. J Diabetes. 2018;doi:10.1111/1753-0407.12816.
Among older Chinese adults with impaired fasting glucose, elevated glucose level together with reduced muscle strength was associated with glycemic…
In the Journals Plus

Checkpoint inhibitors improve survival for metastatic melanoma with brain metastases

Iorgulescu JB, et al. Cancer Immunol Res. 2018;doi:10.1158/2326-6066.CIR-18-0067.
Treatment with checkpoint blockade immunotherapy more than doubled the rate of 4-year OS among patients with melanoma and metastatic brain…
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Delay in bottle-feeding may reduce early childhood obesity risk

Ortega-Garcia JA, et al. Child Obes. 2018;doi:10.1089/chi.2017.0335.
Among children whose introduction to bottle-feeding is delayed, the longer duration of breastfeeding may confer protection against obesity at age 6…
In the Journals Plus

HCV vaccine could reduce transmission in people who inject drugs

Major N, e al. Sci Transl. Med. 2018;doi:10.1126/scitranslmed.aao4496.
A vaccine that would provide incomplete immunity against hepatitis C virus could still reduce the spread of the virus among drug users sharing…
In the Journals Plus

Grapes pressed with infected mice caused tularemia outbreak at German winery

Burckhardt F, et al. N Engl J Med. 2018;doi:10.1056/NEJMc1800353.
The consumption of grape must from fruit that had been accidentally pressed with infected mice appeared to be the cause of a small 2016 outbreak of…
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