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CMV load a potential endpoint in transplant infection trials

Natori Y, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix793.
Although symptomatic cytomegalovirus disease is typically the endpoint in clinical trials involving organ recipients, viral load can act as a…
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Viral hepatitis causes more deaths than HIV, malaria, TB

Naghavi M, et al. Lancet. 2017;doi:10.1016/S0140-6736(17)32152-9.
Despite recent advances in hepatitis C treatment and the availability of hepatitis vaccinations, deaths attributable to viral hepatitis have exceeded…
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Bevacizumab extends survival in advanced cervical cancer

Tewari KS, et al, Lancet. 2017;doi:10.1016/S0140-6736(17)31607-0.
The addition of bevacizumab to chemotherapy continued to show significant survival benefits in women with advanced cervical cancer, according to…
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Routine rapid HCV testing cost-effective in younger generations

Assoumou SA, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix798.
Chhatwal J, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix800.
Routine rapid testing for hepatitis C virus infection among adolescents and young adults was cost-effective when implemented in communities with a…
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Age-related changes in thyroid physiology influence hormone levels

Mammen JS, et al. Thyroid. 2017;doi:10.1089/thy.2017.0211.
Thyroid function is linked with age-related changes in pituitary and thyroid physiology in older adults, according to data recently published in
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Strategies needed to engage younger women with National Diabetes Prevention Program

Ritchie ND, et al. Am J Prev Med. 2017;doi:10.1016/j.amepre.2017.06.013.
Women aged 39 years or younger with prediabetes or past gestational diabetes are half as likely to enroll in a National Diabetes Prevention Program…
In the Journals PlusPerspective

Carbohydrate consumption timing affects glucose, insulin excursions

Shukla AP, et al. BMJ Open Diabetes Res Care. 2017;doi:10.1136/bmjdrc-2017-000440.
Adults with type 2 diabetes who consumed carbohydrates last during their meals had lower glucose peaks and insulin excursions and higher GLP-1…
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Anti-osteoporosis prescription prevalence steadily decreasing in Spain

Martin-Merino E, et al. Bone. 2017;doi:10.1016/j.bone.2017.08.031.
Utilization of anti-osteoporosis therapies increased by 41% from 2001 to 2006 before steadily declining by 63% during the next 7 years, according to…
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Kidney disease ‘virtually universal’ at long durations of type 1 diabetes

Costacou T, et al. Diabetes Care. 2017;doi:10.2337/dc17-1118.
Patients with type 1 diabetes duration of 50 years are more likely than not to experience some form of kidney disease, and although incidence of…
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Dabigatran associated with higher 30-day readmission rate for bleeding than warfarin

Lau WCY, et al. J Thromb Haemost. 2017;doi:10.1111/jth.13780.
Patients treated with dabigatran for nonvalvular atrial fibrillation appeared to be at higher risk for 30-day hospital readmission due to bleeding…
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Adjuvant chemotherapy may improve gastroesophageal cancer survival

Mokdad AA, et al. JAMA Oncol. 2017;doi:10.1001/jamaoncol.2017.2805.
Patients with locally advanced gastroesophageal adenocarcinoma treated with preoperative chemoradiotherapy and resection lived an average of 6 months…
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Rapid diagnostic testing may help tailor gonorrhea treatment

Tuite AR, et al. J Infect Dis. 2017;doi:10.1093/infdis/jix450.
Rapid diagnostics that report an infection’s vulnerability to specific antibiotics may help health care providers extend the use of existing
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Rates of hip fracture, subsequent 1-year mortality differ by race

Liu LH, et al. Am J Manag Care. 2017;23(9):560-564.
The incidence of hip fracture is highest among white men and lowest among Asian men, with Asian men also experiencing lower 1-year mortality risk…
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Maternal TPOAb positivity tied to metabolic syndrome in offspring

Heikkinen AL, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01137.
Children whose mothers are positive for thyroid peroxidase antibodies are more likely to have metabolic syndrome, greater waist circumference and…
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Abdominal obesity with diabetes doubles risk for cognitive impairment

Li Y, et al. J Diabetes Complications. 2017;doi:10.1016/j.jdiacomp.2017.09.006.
Among older Chinese adults with abdominal obesity, having type 2 diabetes more than doubled the risk for developing cognitive impairment, although…

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