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No advantage in adding meropenem to colistin for A. baumannii infections

Paul M, et al. Lancet Infect Dis. 2018;doi:10.1016/S1473-3099(18)30099-9.
Perez F, Bonomo RA. Lancet Infect Dis. 2018;doi:10.1016/S1473-3099(18)30112-9.
Adding meropenem to colistin does not result in better outcomes compared with colistin monotherapy in hospital patients with severe infections caused…
In the Journals Plus

Targeted radiation reduces mortality for early-stage lung cancer

Stokes WA, et al. J Clin Oncol. 2018;doi:10.1200/JCO.2017.75.6536.
Stereotactic body radiation therapy conferred lower 30-day and 90-day mortality rates than surgery among patients with early-stage non-small cell…
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Study identifies racial disparities in multiple myeloma treatment, outcomes

Ailawadhi S, et al. Cancer. 2018;doi:10.1002/cncr.31237.
Outcomes for patients with multiple myeloma treatment appeared to substantially improve in recent years, according to findings published in…
In the Journals Plus

Fluids extend survival at end of life for patients with cancer

Davies AN, et al. Palliat Med. 2018;doi:10.1177/0269216317741572.
Patients with cancer at end of life who received assisted hydration survived nearly 1.5 days longer than those who did not receive fluids, according…
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Xanthine oxidase activity associated with type 2 diabetes risk

Li X, et al. Diabetes Care. 2018;doi:10.2337/dc17-1434.
In both men and women, higher levels of serum xanthine oxidase activity were linked with an increased risk for type 2 diabetes, according to findings…
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Weight loss similar with healthy low-fat, low-carbohydrate diets

Gardner CD, et al. JAMA. 2018;doi:10.1001/jama.2018.0245.
Weight loss over 12 months was substantially the same between adults assigned to a healthy low-fat diet or a healthy low-carbohydrate diet, according…
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Infectious, autoimmune encephalitis show similar incidence, prevalence

Dubey D, et al. Ann Neurol. 2018;doi:10.1002/ana.25131.
Findings recently published in Annals of Neurology indicate that autoimmune encephalitis has an incidence and prevalence similar to that of…
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Extending interferon treatment duration for chronic delta hepatitis improves outcomes

Yurdaydin C, et al. J Infect Dis. 2018;doi:10.1093/infdis/jix656.
Interferon treatment lasting longer than 2 years for chronic delta hepatitis, or CDH, increases virologic response and “favorably affects the…
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Greater CV benefit with canagliflozin vs. other diabetes drugs

Patorno E, et al. BMJ. 2018;doi:10.1136/bmj.k119.
Adults with type 2 diabetes beginning treatment with canagliflozin may have a lower risk for hospital admissions for heart failure, acute myocardial…
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Contaminated HCDs cause up to 282 cases of M. chimaera per year

Sommerstein R, et al. Emerg Infect Dis. 2018;doi:10.3201/eid2403.171554.
Globally, contaminated heater-cooler devices used during cardiac surgery may cause up to 282 cases of invasive Mycobacterium chimaera infection each…
In the Journals PlusPerspective

Exercise can benefit metabolic health in obesity

Do K, et al. BMC Obesity. 2018;doi:10.1186/s40608-018-0183-7.
Adults with mild to severe obesity can obtain metabolic health benefits with physical activity and healthy fitness behaviors while remaining obese…
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Fracture incidence in thyroid cancer linked to levothyroxine dose

Shin DW, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3407.
Adults with thyroid cancer taking less than 115 µg per day or at least 145 µg per day of levothyroxine after thyroidectomy or radioiodine ablation…
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CDC: ‘Complex’ relationship between childhood obesity and parental income, education level

Ogden CL, et al. MMWR Morb Mortal Wkly Rep. 2018;doi:10.15585/mmwr.mm6706a3.
The prevalence of childhood obesity in the United States decreased with increasing level of parental education in 2011-2014; however, the association…
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Current WHO strategy not enough to eliminate yaws, researchers say

Mitjà O, et al. Lancet. 2018;doi:10.1016/S0140-6736(18)30204-6.
Šmajs D, Pospíšilová P. Lancet. 2018;doi:10.1016/S0140-6736(18)30205-8.
A WHO-adopted strategy that aims to eliminate yaws in endemic areas through the mass administration of a single round of azithromycin significantly…
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Statin use does not ‘substantially’ increase risk for influenza

Izurieta HS, et al. Clin Infect Dis.2018;doi10.1093/cidciy4846330.
Researchers have concluded that although high-intensity statin users experienced a greater risk for influenza-related medical encounters after…

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