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No advantage in adding meropenem to colistin for A. baumannii infections

Paul M, et al. Lancet Infect Dis. 2018;doi:10.1016/S1473-3099(18)30099-9.
Perez F, Bonomo RA. Lancet Infect Dis. 2018;doi:10.1016/S1473-3099(18)30112-9.
Adding meropenem to colistin does not result in better outcomes compared with colistin monotherapy in hospital patients with severe infections caused…
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Targeted radiation reduces mortality for early-stage lung cancer

Stokes WA, et al. J Clin Oncol. 2018;doi:10.1200/JCO.2017.75.6536.
Stereotactic body radiation therapy conferred lower 30-day and 90-day mortality rates than surgery among patients with early-stage non-small cell…
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Study identifies racial disparities in multiple myeloma treatment, outcomes

Ailawadhi S, et al. Cancer. 2018;doi:10.1002/cncr.31237.
Outcomes for patients with multiple myeloma treatment appeared to substantially improve in recent years, according to findings published in…
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Fluids extend survival at end of life for patients with cancer

Davies AN, et al. Palliat Med. 2018;doi:10.1177/0269216317741572.
Patients with cancer at end of life who received assisted hydration survived nearly 1.5 days longer than those who did not receive fluids, according…
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Xanthine oxidase activity associated with type 2 diabetes risk

Li X, et al. Diabetes Care. 2018;doi:10.2337/dc17-1434.
In both men and women, higher levels of serum xanthine oxidase activity were linked with an increased risk for type 2 diabetes, according to findings…
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Weight loss similar with healthy low-fat, low-carbohydrate diets

Gardner CD, et al. JAMA. 2018;doi:10.1001/jama.2018.0245.
Weight loss over 12 months was substantially the same between adults assigned to a healthy low-fat diet or a healthy low-carbohydrate diet, according…
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Infectious, autoimmune encephalitis show similar incidence, prevalence

Dubey D, et al. Ann Neurol. 2018;doi:10.1002/ana.25131.
Findings recently published in Annals of Neurology indicate that autoimmune encephalitis has an incidence and prevalence similar to that of…
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Extending interferon treatment duration for chronic delta hepatitis improves outcomes

Yurdaydin C, et al. J Infect Dis. 2018;doi:10.1093/infdis/jix656.
Interferon treatment lasting longer than 2 years for chronic delta hepatitis, or CDH, increases virologic response and “favorably affects the…
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Greater CV benefit with canagliflozin vs. other diabetes drugs

Patorno E, et al. BMJ. 2018;doi:10.1136/bmj.k119.
Adults with type 2 diabetes beginning treatment with canagliflozin may have a lower risk for hospital admissions for heart failure, acute myocardial…
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Contaminated HCDs cause up to 282 cases of M. chimaera per year

Sommerstein R, et al. Emerg Infect Dis. 2018;doi:10.3201/eid2403.171554.
Globally, contaminated heater-cooler devices used during cardiac surgery may cause up to 282 cases of invasive Mycobacterium chimaera infection each…
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Exercise can benefit metabolic health in obesity

Do K, et al. BMC Obesity. 2018;doi:10.1186/s40608-018-0183-7.
Adults with mild to severe obesity can obtain metabolic health benefits with physical activity and healthy fitness behaviors while remaining obese…
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Fracture incidence in thyroid cancer linked to levothyroxine dose

Shin DW, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3407.
Adults with thyroid cancer taking less than 115 µg per day or at least 145 µg per day of levothyroxine after thyroidectomy or radioiodine ablation…
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CDC: ‘Complex’ relationship between childhood obesity and parental income, education level

Ogden CL, et al. MMWR Morb Mortal Wkly Rep. 2018;doi:10.15585/mmwr.mm6706a3.
The prevalence of childhood obesity in the United States decreased with increasing level of parental education in 2011-2014; however, the association…
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Current WHO strategy not enough to eliminate yaws, researchers say

Mitjà O, et al. Lancet. 2018;doi:10.1016/S0140-6736(18)30204-6.
Šmajs D, Pospíšilová P. Lancet. 2018;doi:10.1016/S0140-6736(18)30205-8.
A WHO-adopted strategy that aims to eliminate yaws in endemic areas through the mass administration of a single round of azithromycin significantly…
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Statin use does not ‘substantially’ increase risk for influenza

Izurieta HS, et al. Clin Infect Dis.2018;doi10.1093/cidciy4846330.
Researchers have concluded that although high-intensity statin users experienced a greater risk for influenza-related medical encounters after…

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