Perspective from Peter H.R. Green, MD, MD
June 26, 2019
1 min read

ImmusanT discontinues phase 2 trial of celiac disease vaccine

Perspective from Peter H.R. Green, MD, MD
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ImmusanT announced that it will discontinue its phase 2 global study of Nexvax2, a peptide-based immunomodulatory vaccine intended to treat celiac disease, according to a company press release.

Although Nexvax2 has been found to be safe and well-tolerated, an interim analysis demonstrated that the vaccine did not provide statistically meaningful protection from gluten exposure for patients with celiac disease compared with placebo.

When reached for comment, ImmusanT said that it “is continuing to compile and analyze information regarding the outcome of this study and will be providing an update accordingly.”