September 04, 2012
1 min read

Male gender, age associated with colorectal neoplasia among Hispanic patients

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Colorectal neoplasia was more common among Hispanic men than women and incidence increased with age and having a family history of the disease, according to recent study data.

Researchers conducted a 23-month retrospective review of 745 Hispanic patients (mean age, 58.9 years; 60.5% women) who underwent first-time screening colonoscopies in Puerto Rico. Medical, endoscopic and pathology records were used to determine the prevalence, size, location and histology of colorectal neoplasia (CRN), including adenomas and cancer.

Overall CRN prevalence was 25.1%, and advanced CRN (polyps ≥1 cm and/or with advanced histology) was detected in 4% of the cohort. Men presented with CRN more than women (31.9% vs. 20.6%; adjusted OR=1.76; 95% CI, 1.25-2.47), and they also had more neoplastic polyps (1.81 ± 0.80 vs. 1.51 ± 0.71; P=.007) compared with women.

More men than women also displayed advanced CRN, although the findings did not reach statistical significance (adjusted OR=1.53; 95% CI, 0.68-3.42). Patients with family history of colorectal cancer were almost three times more likely to have advanced CRN (adjusted OR=2.73; 95% CI, 1.10-6.79) than those without family history of colorectal cancer.

Data indicated that 67.7% of neoplasia were located in the proximal colon, and incidence was not significantly different between men and women (71.2% vs. 64.1%; P=.30). CRN increased significantly with age from 23% (patients aged 50-59) to 33.8% (patients aged 70 years and older; P=.007).

“Our research observations confirm ethnic and sex variations on CRN patterns among [Puerto Rican] Hispanic individuals,” the researchers concluded, “implying that screening algorithms for Hispanic individuals should emphasize the importance of colonoscopy as a screening tool.”