VIDEO: Researcher explores role of sex hormones in metabolic health of men transitioning to women
LOS ANGELES — Sex hormones are critically important to modulation of adipose tissue function, metabolism, insulin sensitivity and overall health, said Deborah Clegg, PhD, of Cedars-Sinai Medical Center in Beverly Hills, California, in a video interview.
Estrogens and certain estrogen receptors in fat cells and the brain play a protective role in women’s metabolic health, according to Clegg. She is currently researching how these hormones function in male-to-female transsexual transitioning. A key question is whether estrogens are as crucial to metabolic health in this setting or whether the ratio of androgens to estrogens is more important.