Bone ultrasound better predictor of fracture risk in patients with type 2 diabetes
NASHVILLE, Tenn. - Bone ultrasound may provide better results than DXA when predicting osteoporotic fracture risk in patients with type 2 diabetes, according to study findings presented here.
“DXA has given disappointing results in measuring the risk of fracture in patients with [type 2 diabetes],” the researchers wrote. “In the general population, bone ultrasound has demonstrated a predictive power of osteoporotic fracture equal to that of DXA. The aim of our study was to evaluate the risk of osteoporotic fracture by [bone ultrasound] of the calcaneal bone in patients with [type 2 diabetes].”
Franco Grimaldi, MD, president of the Italian chapter of the American Association of Clinical Endocrinologists, and colleagues at other institutions analyzed data from 108 consecutive patients with diabetes (55 men) and 287 healthy controls (102 men) matched for age and sex. Researchers performed bone ultrasound on the heel of participants, analyzing speed of sound, broadband ultrasound attenuation, stiffness index and the T-score.
Patients with diabetes showed lower T-scores than healthy controls (-0.56 ± 1.38 vs. -0.16 ± 1.18; P = .0004) and a higher BMI. All bone ultrasound parameters, including T-score, were lower for participants who had diabetes and fractures compared with patients with diabetes who did not have fractures (T-score: 1.73 ± 1.28 vs. 0.38 ± 1.31; P = .0001).
“Within the diabetic population, [bone ultrasound] values are significantly lower in subjects with fractures, compared to non-fractured,” the researchers wrote. “The ultrasound of the heel appears to be a promising method for screening for fracture risk in patients with [type 2 diabetes].” - by Regina Schaffer
Grimaldi F, et al. Abstract 2139107. Presented at: AACE 24th Annual Scientific & Clinical Congress; May 13-17, 2015; Nashville, Tenn.
Disclosure: The researchers report no relevant financial disclosures.