November 11, 2014
1 min read

Patients treated with continuous Botox perceived themselves as younger than actual age

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SAN DIEGO — Treatment with Botox during the course of several years was shown to be safe, even in conjunction with other aesthetic treatments. Additionally, patients who received continuous treatment perceived themselves to look younger than their actual age, according to a speaker here.

During the American Society for Dermatologic Study Annual Meeting, Alastair Carruthers, FRCPC, presented the results of an international, retrospective chart review including 194 patients who were 18 years or older at the time of their first Botox (onabotulinumtoxin-A, Allergan) aesthetic treatment and had at least 5 years’ history of continuous treatment.

Carruthers and colleagues reviewed patient records between 1999 and 2012 to evaluate the facial areas treated with onabotulinumtoxin-A, the number of treatments performed, the dosage per facial treatment area, concomitant facial aesthetic procedures and treatments, and any treatment-related adverse events.

“We wanted to look at real life, how this treatment has been incorporated into patients’ lives and how the treatments themselves have changed over time,” Carruthers said.

Data were collected from a total of 5,112 treatment sessions, with an average of two or more treatments annually for a mean of 9.1 years. Carruthers and colleagues found the mean age at first injection was 46.3, and the longer patients were treated, the younger they perceived themselves to appear.

Although dosing for glabellar lines and crow’s feet lines remained stable during the study period, the researchers found dosing for horizontal forehead lines had decreased since 1999.

“Doctors now use less Botox per treatment session to treat horizontal forehead lines,” Carruthers said. “We are now able produce a more natural result.”

Over time, patients in the study received additional noninvasive facial aesthetic treatments, including energy-based procedures. Adverse effects were found to be infrequent when onabotulinumtoxin-A treatments were combined with other facial aesthetics procedures, according to Carruthers.

Carruthers emphasized the importance of seeking an expert, such as a dermatologist or dermatologic surgeon, for wrinkle-relaxing cosmetic medical procedures.


Carruthers A. Evolution of facial aesthetic treatment over five or more years: An international retrospective, cross-sectional analysis of continuous Onabotulinumtoxin-A treatment. Presented at: American Society for Dermatologic Study Annual Meeting. Nov. 6-9, 2014; San Diego.