Atherosclerotic risk factors increase as patients age
The number of atherosclerotic risk factors a patient had increased with age, according to data presented at the International Stroke Conference.
Sharon N. Poisson, MD, associate professor, co-director of stroke services and director of the vascular neurology fellowship in the department of neurology at University of Colorado School of Medicine in Aurora, and colleagues analyzed data from 141 children and 449 young adults who had an ischemic stroke and were cared for between 2000 and 2014. Control groups were also selected for children (n = 354) and young adults (n = 1,014).
Atherosclerotic risk factors that were assessed in this study include diabetes, hypertension, hyperlipidemia, smoking history and obesity.
Children with stroke and controls had very low rates of atherosclerotic risk factors. The odds of stroke increased in patients aged 20 to 29 years with hypertension and more than one risk factor.
All five risk factors increased the odds of having a stroke in patients aged 30 to 39 years and 40 to 49 years. This was also seen in participants with more than one atherosclerotic risk factor.
“[Atherosclerotic risk factors] are very rare in children, including in those with strokes,” Poisson and colleagues wrote. “Hypertension begins to increase the odds of stroke in the decade of life, but in the and decades, each risk factor’s impact on stroke risk is significant, with more than one risk factor increasing the odds of stroke 10-fold.” – by Darlene Dobkowski
Poisson SN, et al. Session A36: Community/Risk Factors Oral Abstracts II. Presented at: International Stroke Conference; Feb. 6-8, 2019; Honolulu.
Disclosures: The authors report no relevant financial disclosures.