Smoking, hypertension among risk factors in young patients with recurrent MI
Young patients who had recurrent MI were more likely to be men, were older at age of index MI, had a history of smoking, hypertension, chronic kidney disease and had a family history of CAD, according to findings presented at the American College of Cardiology Asia Conference.
“The various modifiable risk factors noted in this study will help in planning appropriate preventive programs to target the younger age group,” Joanne Karen Recacho-Turingan, MD, cardiology fellow at The Medical City in Manila, the Philippines, told Cardiology Today. “This should be highlighted as this will provide benefit for our young patients. Emphasis for the young population should be targeted at better control of hypertension, dyslipidemia and diabetes mellitus and in addition, smoking habits and control of obesity.”
To develop a clinical profile of young people who were most likely to have recurrent MI, researchers analyzed data on clinical risk factors from 133 patients aged 45 years or younger with acute MI who were admitted to The Medical City between 2013 and 2016.
During the study period, 22 patients (100% men; mean age, 40.9 years) had recurrence and 111 did not (90.1% men; mean age, 39.6 years).
In those with recurrence, researchers determined that non-STEMI was more common than STEMI (68.2% vs. 31.8%) and that chest pain was the most frequent presenting symptom (81.8%). Most patients with recurrence also presented with unstable vital signs (90.9%) at the time of admission.
In addition, researchers concluded that positive smoking history (81.8%; P = .074), hypertension (95.5%; P =.007), family history (59.1%; P = .115) and chronic kidney disease (13.6%; P = .023) were more likely in those with recurrence than in those without.
“Heart attack in young patients can cause disability and even death at the prime of life,” Recacho-Turingan said in a press release. “There are often serious consequences for these patients, their families and the health system, which can lead to an increased economic burden. We must make sure to work with these patients on their modifiable risk factors to reduce their risk not just for a second heart attack, but hopefully, even preventing the first.” – by Melissa J. Webb
Recacho-Turingan JK, et al. Clinical profile of recurrent myocardial infarction in the young. Presented at: American College of Cardiology Asia Conference. Nov. 30-Dec. 2, 2018; Shanghai.
Disclosure: Recacho-Turingan reports no relevant financial disclosures.