May 14, 2013
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Cardiogenic shock increased mortality risk in primary PCI

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Thirty-day all-cause mortality was higher in patients presenting with cardiogenic shock who were treated with primary PCI for acute MI caused by an unprotected left main coronary artery culprit lesion vs. those who did not have cardiogenic shock.

“This meta-analysis is the first of its kind and may serve as a benchmark for [patients with] left main coronary artery-related acute MI presenting with cardiogenic shock,” trial investigator José P.S. Henriques, MD, PhD, told Cardiology Today’s Intervention.

 

José P.S. Henriques

Henriques and colleagues examined 13 retrospective cohort studies reporting on patients presenting with primary PCI for unprotected left main coronary artery culprit lesion-related acute MI. No randomized trials met the prespecified criteria for the meta-analysis.

A total of 977 patients were examined, of whom 252 (26%) presented with cardiogenic shock. The researchers evaluated 30-day all-cause mortality using a forest plot analysis.

Henriques and colleagues concluded that the average estimated 30-day all-cause mortality was 55% for patients with cardiogenic shock and 15% for patients presenting without signs of cardiogenic shock (RR=3.74; 95% CI, 2.95-4.76). The results were not affected by stent type.

Disclosure: Henriques reports no relevant financial disclosures.