December 23, 2015
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Higher levels of physical activity associated with poorer asthma control in young females

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Patients with asthma had higher levels of activity compared with patients in a control group, with females who had poor asthma control displaying higher levels of activity compared with males in the study, according to recent research published in Respirology.

“It is important to remember that the high level of activity means nothing extreme — in our patient material every third girl exercised that much,” Ludvig Lövström, from the department of medical sciences and clinical physiology at Uppsala University, Uppsala, Sweden, stated in a press release. “Still, we uncovered these results, and with such a distinct sex difference.”

Lövström and colleagues evaluated 408 asthma patients and 118 controls aged between 10 years and 34 years who underwent the Asthma Control Test, exhaled nitric oxide test, methacholine challenges and spirometry to measure asthma control. In addition, patients answered questions about their physical activity.

The researchers found that patients with asthma were physically active more frequently (P = .01) and the duration of activity for these patients was also longer (P = .002) than patients in the control group, according to the abstract. When activity was measured by sex, Lövström and colleagues found that male patients with asthma had better frequency (P = .02) and duration (P = .03) of activity than males in the control group; however, there was no significant difference between physical activity frequency or duration for females in the asthma or control groups.

Among female patients with asthma, poor asthma control was associated with higher levels of activity, with females who were frequently physically active having an OR of 4.81 for displaying poor asthma control compared with females who were only moderately physically active (95% CI, 2.43–9.51). Similarly, females with a high duration of physical activity were more likely to have poorer asthma control compared with female patients with a moderate duration of physical activity (OR = 3.89; 95% CI, 2.00–7.59). – by Jeff Craven

Disclosure: Borres is a paid employee of Thermo Fisher Scientific.