Risk of hyperkalemia and organ transplant recipients

Solid organ transplant recipients who develop hyperkalemia have an increased risk of mortality and 30-day readmissions, according to University of Cincinnati researchers led by Charuhas Thakar, MD.

“The study examined all acute care hospitalizations in transplant recipients based on a national cohort,” Thakar, professor and director of the UC Division of Nephrology Kidney CARE Program at the UC College of Medicine told Nephrology News & Issues.

After adjustment for major confounders, researchers analyzed the effect of hyperkalemia and its severity on in-hospital mortality/hospice discharge and 30-day readmissions.

Among approximately 15,000 solid organ transplant recipients, results showed 16% experienced hyperkalemia. Researchers found an overall in-hospital mortality of 2.6%, with a mortality rate of 6.1% and 2% in patients with vs. without hyperkalemia, respectively. Patients with hyperkalemia experienced an increased risk of death and 30-day readmissions, according to results. – by Casey Tingle

Disclosure: Thakar reports that part of the research was supported by a fellowship grant award funded by Relypsa.

Solid organ transplant recipients who develop hyperkalemia have an increased risk of mortality and 30-day readmissions, according to University of Cincinnati researchers led by Charuhas Thakar, MD.

“The study examined all acute care hospitalizations in transplant recipients based on a national cohort,” Thakar, professor and director of the UC Division of Nephrology Kidney CARE Program at the UC College of Medicine told Nephrology News & Issues.

After adjustment for major confounders, researchers analyzed the effect of hyperkalemia and its severity on in-hospital mortality/hospice discharge and 30-day readmissions.

Among approximately 15,000 solid organ transplant recipients, results showed 16% experienced hyperkalemia. Researchers found an overall in-hospital mortality of 2.6%, with a mortality rate of 6.1% and 2% in patients with vs. without hyperkalemia, respectively. Patients with hyperkalemia experienced an increased risk of death and 30-day readmissions, according to results. – by Casey Tingle

Disclosure: Thakar reports that part of the research was supported by a fellowship grant award funded by Relypsa.