In the Journals

Bariatric surgery associated with protective effects against AKI

According to a study with a median follow-up of 2.9 years that was published in BMJ Open, bariatric surgery was linked with protective effects against acute kidney injury. Although investigators found an increased risk of acute kidney injury within the first 30 days after surgery, they noted the overall effect of the procedure on the incidence of acute kidney injury was beneficial.

Uwe Koppe

“Bariatric surgery is an important method in weight management, with well-established benefits for vascular and diabetes outcomes,” Uwe Koppe, PhD, lead author of the study from the Robert Koch-Institut, told Healio Nephrology. “Here, we were able to show for the first time that it is associated with protective effects on acute kidney injury during long-term follow-up.”

The propensity-matched cohort study of patients from the U.K. Clinical Practice Research Datalink database included 2,643 patients who had bariatric surgery and 2,595 patients without the surgery.

“Results were compatible with an increased risk of AKI in the first 30 days following surgery compared with patients without surgery, but AKI incidence was substantially decreased in patients with bariatric surgery during long-term follow-up (rate ratio 0.37, 95% CI 0.23 to 0.61) even after accounting for chronic kidney disease status at baseline. Over the whole period of follow-up, bariatric surgery had a net protective effect on risk of AKI (rate ration 0.45, 95% CI 0.28 to 0.72),” the researchers wrote.

 

Disclosures: The authors reported no relevant financial disclosures.

According to a study with a median follow-up of 2.9 years that was published in BMJ Open, bariatric surgery was linked with protective effects against acute kidney injury. Although investigators found an increased risk of acute kidney injury within the first 30 days after surgery, they noted the overall effect of the procedure on the incidence of acute kidney injury was beneficial.

Uwe Koppe

“Bariatric surgery is an important method in weight management, with well-established benefits for vascular and diabetes outcomes,” Uwe Koppe, PhD, lead author of the study from the Robert Koch-Institut, told Healio Nephrology. “Here, we were able to show for the first time that it is associated with protective effects on acute kidney injury during long-term follow-up.”

The propensity-matched cohort study of patients from the U.K. Clinical Practice Research Datalink database included 2,643 patients who had bariatric surgery and 2,595 patients without the surgery.

“Results were compatible with an increased risk of AKI in the first 30 days following surgery compared with patients without surgery, but AKI incidence was substantially decreased in patients with bariatric surgery during long-term follow-up (rate ratio 0.37, 95% CI 0.23 to 0.61) even after accounting for chronic kidney disease status at baseline. Over the whole period of follow-up, bariatric surgery had a net protective effect on risk of AKI (rate ration 0.45, 95% CI 0.28 to 0.72),” the researchers wrote.

 

Disclosures: The authors reported no relevant financial disclosures.