Meeting News

Likelihood of renal recovery after AKI varies based on sex, race

Silvi Shah

WASHINGTON — Data presented here at ASN Kidney Week showed patients who developed ESKD due to acute kidney injury had different outcomes based on sex and race.

“Acute kidney injury requiring dialysis is a contributor to the growing burden of end-stage kidney disease,” Silvi Shah, MD, MS, FACP, FASN, assistant professor in the division of nephrology at the University of Cincinnati, said during a presentation. “Little is known about the frequency and patterns of recovery of AKI and its impact on mortality in incident dialysis patients.”

Researchers used the United States Renal Data System to identify patients who developed ESKD after having AKI. Investigators determined 1-year mortality rates and considered the impact of sex and race on rates of recovery and long-term outcomes.

They found 1-year all-cause mortality was 21.8%, with ESKD due to AKI conferring a higher risk of mortality in the first 12 to 24 months compared with ESKD due to diabetes or other causes.

When evaluating patients who did recover renal function (35.3% of the study population; median time of recovery, 2 months), researchers discovered women had a 14% lower likelihood of recovery than men. In addition, black, Asian, Hispanic and Native American patients a lower likelihood of renal recovery than white patients.

She concluded, “Renal models of care and therapies are important to deliver appropriate dialysis care to patients with AKI and to promote renal recovery.” – by Melissa J. Webb

Reference:

Shah S, et al. Abstract FR-OR016. Presented at: ASN Kidney Week; Nov. 7-10, 2019; Washington D.C.

Disclosure: Shah reports no relevant financial disclosures.

Silvi Shah

WASHINGTON — Data presented here at ASN Kidney Week showed patients who developed ESKD due to acute kidney injury had different outcomes based on sex and race.

“Acute kidney injury requiring dialysis is a contributor to the growing burden of end-stage kidney disease,” Silvi Shah, MD, MS, FACP, FASN, assistant professor in the division of nephrology at the University of Cincinnati, said during a presentation. “Little is known about the frequency and patterns of recovery of AKI and its impact on mortality in incident dialysis patients.”

Researchers used the United States Renal Data System to identify patients who developed ESKD after having AKI. Investigators determined 1-year mortality rates and considered the impact of sex and race on rates of recovery and long-term outcomes.

They found 1-year all-cause mortality was 21.8%, with ESKD due to AKI conferring a higher risk of mortality in the first 12 to 24 months compared with ESKD due to diabetes or other causes.

When evaluating patients who did recover renal function (35.3% of the study population; median time of recovery, 2 months), researchers discovered women had a 14% lower likelihood of recovery than men. In addition, black, Asian, Hispanic and Native American patients a lower likelihood of renal recovery than white patients.

She concluded, “Renal models of care and therapies are important to deliver appropriate dialysis care to patients with AKI and to promote renal recovery.” – by Melissa J. Webb

Reference:

Shah S, et al. Abstract FR-OR016. Presented at: ASN Kidney Week; Nov. 7-10, 2019; Washington D.C.

Disclosure: Shah reports no relevant financial disclosures.

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