Researchers discovered fluoroquinolone-resistant Escherichia coli in 8.8% of fecal samples collected from healthy adult women with no recent documented UTI, mostly from two pandemic strains, according to findings published in Clinical Infectious Diseases.
“The two E. coli strains that cause the vast majority of Cipro- and multidrug-resistant (MDR) urinary and bloodstream infections in the United States and globally are actually superb gut colonizers of healthy women that did not experience UTI for at least a year and do not take antibiotics,” Evgeni V. Sokurenko, MD, PhD, professor of microbiology at the University of Washington School of Medicine, told Infectious Disease News. “Thus, the pandemic MDR E. coli, once emerged, can circulate in the community as asymptomatic gut colonizers with a very high persistency.”
This activity is supported by educational grants from AbbVie, Inc.; Pfizer, Inc.; and Takeda Pharmaceuticals U.S.A., Inc.
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