Smoking electronic cigarettes provokes changes in soluble CD40-ligand, soluble P-selectin and platelet function in smokers and nonsmokers in ways that are similar to the smoking of tobacco cigarettes, according to a study published in The American Journal of Cardiology.
“This is the first study to examine the effect of exposure to both conventional tobacco cigarettes and e-cigarettes on platelet function in vivo,” Cristina Nocella, PhD, of IRCCS NeuroMed in Pozzilli, Italy, and colleagues wrote. “In smokers and nonsmokers without cardiovascular disease, use of both products leads to an increase in platelet activation. The effects of e-cigarettes were less pronounced than those of [tobacco] cigarettes in nonsmokers. Conversely, the effect of e-cigarettes in smokers showed a less detrimental impact than [tobacco] cigarettes but only for platelet aggregation.”
This activity is supported by educational funding provided by Amarin Pharma Inc., Amgen, and Quest Diagnostics.
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