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2 studies underscore high CV risk in primary aldosteronism, despite treatment

November 21, 2017

Patients with primary aldosteronism have markedly increased risk for cardiovascular and cerebrovascular events, including stroke and coronary artery disease, compared with those with essential hypertension, and that risk persists even with mineralocorticoid antagonist therapy, according to two analyses published in The Lancet Diabetes & Endocrinology.

The association was independent from blood pressure level, age and sex, suggesting that aldosterone can induce CV effects through mechanisms that are at least partly independent of its effects on BP, according to the researchers.

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Focus on Managing Patients with Chronic Heart Failure

This activity is supported by an independent educational grant from Novartis Pharmaceuticals Corporation.

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