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Parkinson’s disease proteins linked to upper GI infections

Parkinson’s disease proteins linked to upper GI infections
June 27, 2017

Alpha-Synuclein, a nerve cell protein linked to Parkinson’s disease and other neurogenerative diseases, appears to induce an immune response in patients with upper GI infection, according to a new observational study.

The findings suggest that frequent or chronic upper GI infections could impair the body’s ability to clear alpha-Synuclein that accumulates in the enteric nervous system, which is then trafficked from the gut to the brain, and could thus contribute to the pathogenesis and progression of Parkinson’s disease, according to study investigators.

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Differentiating and Managing Diarrhea: A Persistent Dilemma

This activity is supported by an educational grant from Romark, L.C.

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