Pharmacology Consult

Hepatitis B vaccine shortage: Unknown impact on future disease

Infectious Disease News, August 2019
Kimberly Boeser, PharmD, MPH, BCIDP
Drug shortages continue to inundate our health care system. They have paralyzed pharmacies and affected hundreds of thousands of patients. Although…


ACIP recommends ‘shared clinical decision-making’ for HPV, pneumococcal vaccines

Infectious Disease News, August 2019
The CDC’s Advisory Committee on Immunization Practices, or ACIP, recommended that HPV and pneumococcal vaccination in older patients be…


Migrants detained at border will not be vaccinated against flu

August 21, 2019
Medical professionals caring for migrant children and their families in holding at the southern border will not vaccinate them against influenza in…

In the Journals

Military combat service linked to an increase in HBV exposure

August 21, 2019
The prevalence of exposure to hepatitis B among veterans was highest among those with traditional risk factors and independently related to military…

UK loses measles elimination status, health officials announce

August 19, 2019
The United Kingdom has lost the measles elimination status it achieved in 2017, health officials announced. The announcement followed what Public…

In the Journals

Herd immunity drives down invasive pneumococcal disease in adults

August 18, 2019
Herd immunity generated by the introduction of the 13-valent pneumococcal conjugate vaccine in the United States — first in 2010 for children…

In the JournalsPerspective

PCV13 serotypes cause nearly 25% of invasive pneumococcal disease in kids

August 16, 2019
Serotypes included in the 13-valent pneumococcal conjugate vaccine, or PCV13, continued to cause nearly 25% of invasive pneumococcal disease, or IPD…

In the Journals

Flu vaccine associated with reduced risk for death, stroke in elderly ICU survivors

August 15, 2019
In Denmark, elderly ICU survivors who received an influenza vaccine had an 8% decreased risk for death and a 16% reduced risk for hospitalization for…

FDA News

Pretomanid, first TB drug developed by non-profit, gets FDA approval for resistant infections

August 14, 2019
The FDA has approved pretomanid — the first tuberculosis drug developed by a non-profit organization — as part of a three-drug regimen…

In the Journals

20% of adults with injection drug use have been infected with HBV

August 11, 2019
Hepatitis B infection rates among adults with a history of injection drug use are more than four times higher than those of the general population…

In the Journals

More than half of preterm infants undervaccinated at age 19 months

August 7, 2019
Research published in Pediatrics suggested that more than 50% of infants born preterm in Washington State did not receive all recommended…

GSK hands rights to Ebola, Marburg vaccines to Sabin Vaccine Institute

August 6, 2019
GSK has transferred the rights to three experimental vaccines against the deadly Ebola and Marburg viruses to the Sabin Vaccine Institute, a…

In the Journals

BCG shows better than expected protection in study of household TB contacts

August 6, 2019
An estimated 25% of household tuberculosis case contacts in the Innate Factors and Early Clearance of Mycobacterium tuberculosis, or INFECT, study…

In the JournalsPerspective

Rotavirus recommendations leave NICU population vulnerable, study finds

August 6, 2019
The CDC’s Advisory Committee on Immunization Practices cautions against administering the rotavirus vaccine to infants in a NICU or nursery…

In the Journals

Patients treated for TB experience higher mortality than general population

August 5, 2019
Tuberculosis is treatable and curable, but newly published study findings showed that patients treated for — or cured of — TB still…

In the Journals

AMAZES: Azithromycin may increase antibiotic resistance in severe asthma

August 2, 2019
In a substudy of the AMAZES trial, azithromycin, when used as a treatment for exacerbations in patients with severe asthma, reduced Haemophilus

Q&A: Insights from recreating the 1918 flu virus

July 31, 2019
In a review published in Science Translational Medicine, researchers summarized key findings and unanswered questions from the 1918 influenza…

In the JournalsPerspective

Prompt NAI treatment reduced hospital stays by 19% during last flu pandemic

July 29, 2019
Neuraminidase inhibitor treatment initiated upon hospitalization decreased patients’ length of stay by 19% overall during the 2009-2010…

In the Journals

Malaria vaccine protects against severe malaria 7 years after vaccination

July 28, 2019
The malaria vaccine RTS,S provides sustained protection against severe malaria 7 years after immunization, according to extended findings from a…

Sanofi Pasteur says flu vaccine shipments to be delayed 1 month

July 26, 2019
Sanofi Pasteur, the largest provider of influenza vaccines in the United States, said shipments of its vaccines for the 2019-2020 season will be…