In the Journals

Xeljanz appears safe for UC treatment despite herpes zoster risk

November 29, 2018
Xeljanz — a small-molecule Janus kinase inhibitor — appeared safe for the treatment of patients with moderate-to-severe ulcerative…

Perspective

Measles cases surge 31%, driven by gaps in vaccination coverage

November 29, 2018
Measles cases surged by 31% worldwide in 2017 — a troubling increase driven by gaps in vaccination coverage that have caused outbreaks of the…

Eye on ID

Ebola: At last, promising agents for prevention and therapy

Infectious Disease News, November 2018
Donald Kaye, MD, MACP; Thomas M Yuill, PhD
Ebola, or more properly, Ebola virus disease (EVD) — the disease that horror writers dream about — is caused by members of a family of…

Feature

Can the CUBE isolation unit be of use in the US?

Infectious Disease News, November 2018
Donald Kaye, MD, MACP; Keith S Kaye, MD, MPH
The CUBE as described in the accompanying article may have applications in highly industrialized countries such as the United States. Of course…

Vir, Alnylam initiate phase 1/2 study of hepatitis B therapy

November 28, 2018
Vir Biotechnology, Inc. and Alnylam Pharmaceuticals, Inc. announced the initiation of a phase 1/2 study of VIR-2218, an investigational RNA…

In the Journals

Fractional dose of yellow fever vaccine confers long-term immunity

November 26, 2018
Administration of a one-fifth dose of yellow fever vaccine resulted in long-term protection against the virus, according to data published in Annals

In midst of outbreak, DRC begins first multidrug trial for Ebola treatments

November 26, 2018
A pioneering randomized control trial evaluating the effectiveness and safety of drugs used to treat patients infected with Ebola virus has begun in…

In the JournalsPerspective

Prior head, neck surgery associated with Streptococcus pneumoniae meningitis

November 26, 2018
Prior head or spine surgery is associated with an increased risk for Streptococcus pneumoniae meningitis beyond the 30-day postoperative period…

One-third of parents are declining flu vaccination for their child this year

November 20, 2018
A C.S. Mott Children’s Hospital National Poll on Children’s Health demonstrated that a significant number of parents choose not to…

Cell-based flu vaccine 36% more effective than egg-based vaccine

November 20, 2018
Seqirus released adjusted data showing that its cell-based quadrivalent influenza vaccine was around 36% more effective than the standard egg-based…

Meeting NewsVideo

VIDEO: ‘Excited about developments in influenza vaccine’

November 19, 2018
“We’re really excited about the developments in influenza vaccine right now,” Creech said. Creech, who is also the director of the…

In the Journals

14 million additional adolescents needed to reach HPV vaccination goal

November 19, 2018
HPV vaccination rates among adolescents must increase substantially for the American Cancer Society to achieve its goal of 80% prevalence by 2026…

In the Journals

Algorithm outperforms radiologists in detecting active pulmonary TB

November 17, 2018
Researchers developed an automated algorithm that was able to detect active pulmonary tuberculosis on chest radiographs better than all groups of…

Cover Story

‘It’s complicated’: Nasal spray or flu shot for pediatric vaccination?

Infectious Diseases in Children, November 2018
After recommending against the live-attenuated influenza vaccine, or LAIV, for 2 years in a row, the CDC’s Advisory Committee on Immunization…

At Issue

Is it appropriate to recommend a reformulated vaccine without additional effectiveness data?

Infectious Diseases in Children, November 2018
In February, the CDC’s Advisory Committee on Immunization Practices recommended a reformulated version of the FDA-approved live-attenuated

Meeting News

Takeda dengue vaccine candidate may protect against all four serotypes

November 14, 2018
Preliminary data regarding a live-attenuated tetravalent dengue vaccine candidate developed by Takeda show that the vaccine may be able to protect…

Meeting News

HBV rates rising in women from same U.S. regions with drug-related HCV

November 12, 2018
SAN FRANCISCO — U.S. states in the Appalachian region demonstrated increased rates of hepatitis B among women despite overall national rates of…

Hepatitis A outbreaks in 2017 linked to drug use, homelessness

November 5, 2018
Significant incidents of hepatitis A outbreaks occurred through direct person-to-person transmission among drug users and homeless individuals during…

Meeting News

Cancer survivors likely to receive HPV vaccine after provider recommendation

November 5, 2018
ORLANDO, Fla. — A study presented at the AAP National Conference & Exhibition revealed that among young adult and adolescent cancer

Fearing cross-border spread, Uganda to start vaccinating against Ebola

November 2, 2018
Uganda will begin vaccinating heath care and other front-line workers against the Ebola virus next week amid concerns that a large outbreak in…