Infectious Disease News

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The following articles appeared in the print edition of INFECTIOUS DISEASE NEWS.

Table of Contents

Q&A: Antiretroviral stewardship in inpatient practice

Vaccine exemption rate rises among US kindergarteners

Researchers ‘encouraged’ by early data from universal flu vaccine study

Policy matters: Anti-LGBT legislation associated with lower rates of HIV testing, awareness

Despite sick leave policies, many health care personnel work while ill

New CAP guidelines stress de-escalation

Q&A: Improving clinical trial design for gonorrhea treatment

Xofluza reduces risk for flu by 86% in household contacts

M. bovis TB detected in Michigan deer hunters

‘Handshake stewardship’ effective and sustainable

WHO: 7 million people diagnosed and treated for TB in 2018

WHO: Ebola outbreak still a global public health emergency

‘A great achievement’: Wild poliovirus type 3 eradicated globally

At Issue

Should doxycycline be used as PrEP for STD prevention?

Cover Story

‘Paying the price for decades of inattention’: STDs resurge in US

Editorial

A stewardship send-off: Optimizing antimicrobials upon discharge

Cynthia T. Nguyen, PharmD; Jerod Nagel, PharmD

Eye on ID

Leptospirosis: A challenging diagnosis

Donald Kaye, MD, MACP

FDA News

FDA advisory committee supports approval of cefiderocol for complicated UTIs

FDA approves Descovy for HIV PrEP, excluding cisgender women

Feature

‘Like insects in amber’: ART ‘freezes’ latent HIV reservoir

Wireless device that transmits OPAT data to doctors wins $10K prize at IDWeek

Shingrix, Zostavax show promise against herpes zoster in patients with cancer

Recent laxative use should not preclude testing patients for C. difficile

Q&A: What providers need to know about congenital rubella syndrome

Most physicians lack on-site antimicrobials for treating gonorrhea and syphilis

NIH announces ‘focused roadmap’ to address rise in tick-borne diseases

How common is pneumococcal urinary antigen testing?

Hooked on ID

Hooked on ID with Elizabeth Connick, MD

In the Journals

Is social media reinforcing gender disparities among researchers?

Maribavir shows promise against CMV in transplant recipients

Maternal HIV infection may impact flu vaccine response in infants

Most pregnant women do not get flu, Tdap vaccines

IV iron does not increase risk for infection, mortality

Public reporting may impede access to valve surgery in endocarditis

Interventions push NICU vaccination coverage beyond 90%

Shared patient rooms noninferior to private rooms for halting ESBL transmission

Study demonstrates long-term success of kidney transplants between people with HIV

HIV controllers at risk for false-negative rapid test results

Surveillance misses many SSIs after outpatient procedures

Tesamorelin ‘very promising’ for reversing liver disease in people with HIV

Use of high-risk antibiotics correlates with more hospital-associated CDI

Not just Lyme: 22% of blacklegged ticks collected on Long Island carry multiple pathogens

Long courses of antibiotics harm infant gut, promote resistance

Xpert Ultra assay identifies pediatric TB with high sensitivity

Cost of congenital syphilis hospitalizations skyrockets with increase in cases

Chlamydia increases risk for PID, ectopic pregnancy, female infertility

Current method of calculating SSIs underestimates rates of some procedures

Ebola, Marburg viruses circulate among bats in India

Experimental TB vaccine could have ‘vast’ impact

CAUTI rates decline after case definition revision, value-based incentive programs

Broad-spectrum antibiotics may weaken flu vaccine response

Fluoroquinolone use decreases following FDA black box warning

Antibiotics commonly dispensed without prescription in China

Booster doses of yellow fever vaccine may be warranted

HBV exposure 4 times higher among female vs. male meth users

HIV care in EDs constitutes an important strategy

72-hour time-out encourages de-escalation of broad-spectrum antibiotics

In pregnant women on ART, safer to initiate isoniazid after delivery

Meeting News

Antibiotic-free or organic poultry half as likely to contain MDR Salmonella

RBX2660 safe, efficacious for recurrent C. difficile prevention

Valacyclovir reduces rate of fetal CMV infection by 71%

C. auris outbreak spreads in 9 California health facilities after single introduction

VIDEO: Experts spend 'a day on the Hill' during IDWeek

VIDEO: Tracking flu in the community as an 'early alert system' for hospitals

Cefiderocol noninferior to high-dose meropenem in phase 3 trial for nosocomial pneumonia

Cell- and egg-based flu vaccines provide similar immunogenicity, surprising researchers

Trivalent HBV vaccine noninferior to monovalent vaccine in adults

Integrase inhibitor-based ART may increase risk for diabetes

51% of early cases in NY measles outbreak attributed to unvaccinated adults

HIV testing increases 15-fold among teens after improvement initiative

MSM using Grindr take more sex risks, also more likely to use HIV PrEP

Febrile seizures following vaccination do not affect development, behavior

Flu vaccine reduces risk for hospitalization in kids, death in adults

H. pylori resistance to clarithromycin doubles in Europe

HCV vaccine regimen fails to prevent chronic infections

Kids’ treatment for acute gastroenteritis in ED depends on race, study shows

Pharmacology Consult

The coming of age of rapid ART initiation in HIV

Jeff Brock, PharmD, MBA, BCPS-AQ ID