EXPERT SUMMARIES of the top 30 journals in infectious disease
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In the Journals Plus

HIV-infected Hispanics at greater risk for HPV-related cancers

Ortiz A, et al. Cancer. 2018;doi:10.1002/cncr.31702.
HIV-infected Hispanic adults in the United States demonstrated a higher risk for HPV-related cancers than Hispanics who did not have HIV, according…
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Depleted plasma gelsolin linked to severe pneumonia outcomes

Self WH, et al. Clin Infect Dis. 2018;doi:10.1093/cid/ciy1049.
Researchers found that a lower concentration of plasma gelsolin, or pGSN, was associated with more severe clinical outcomes in adults hospitalized…
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Meningococcal B vaccine Bexsero may protect against gonorrhea

Semchenko EA, et al. Clin Infect Dis. 2018;doi:10.1093/cid/ciy1061.
Bexsero, a meningococcal B vaccine approved in the United States since 2015, induces antibodies in humans that target Neisseria gonorrhoeae
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Study: Probiotics do not reduce C. difficile in hospitalized patients

Box MJ et al. Open Forum Infect Dis. 2018;
A large retrospective cohort study showed that probiotics did not decrease rates of facility-onset Clostridioides difficile in hospitalized patients…
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Schistosomiasis associated with HIV transmission, death

Wall KM, et al. PLoS Negl Trop Dis. 2018;doi:10.1371/journal.pntd.0006902.
Researchers found that schistosome infection was associated with increased transmission of HIV from both men and women in Zambia, as well as HIV…
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Morocco sees 16% annual decline in leprosy cases attributed to rifampicin

Khoudri I, et al. PLoS Negl Trop Dis. 2018;doi:10.1371/journal.pntd.0006910.
Leprosy cases in Morocco declined by 16% annually from 2012 to 2017 after the implementation of single-dose rifampicin chemoprophylaxis, researchers…
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Vaccination halves risk for flu-related hospitalization among adults

Ferdinands JM, et al. J Infect Dis. 2018;doi:10.1093/infdis/jiy723.
Vaccination halved the risk for influenza-associated hospitalization among adults during the 2015-2016 influenza season in the United States, most of…
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Community-acquired respiratory viruses a risk factor for chronic lung allograft dysfunction

Peghin M et al. Clin Infect Dis. 2018;
Community-acquired respiratory viruses causing lower respiratory tract infections are a significant independent risk factor for the development of…
In the Journals Plus

Patients with cancer have 40% higher risk for shingles

Kawai K and Yawn BP. J Infect Dis. 2018;doi:10.1093/infdis/jiy626.
Qian J, et al. J Infect Dis. 2018;doi:10.1093/infdis/jiy625.
Patients diagnosed with cancer of any kind have an approximately 40% higher risk for developing shingles than patients without cancer, researchers…
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Adenovirus causes keratoconjunctivitis outbreak at eye clinic

OYong K, et al. MMWR Morb Mortal Wkly Rep. 2018;doi:10.15585/mmwr.mm6748a4.
A 2017 outbreak of epidemic keratoconjunctivitis at an eye care clinic in Los Angeles was caused by a novel human adenovirus type, according to study…
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Treatment bundle leads to ‘dramatic improvement’ in UTI management

MacLaggen TD, et al. Infect Control Hospit Epidemiol. 2018;doi:10.1017/ice.2018.276.
A UTI management bundle implemented at a Canadian hospital resulted in a “dramatic improvement” in the management of UTIs, including…
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Higher RPR titers, recent diagnosis predict syphilis treatment response

Spagnuolo V, et al. Open Forum Infect Dis. 2018;
Higher rapid plasma reagin, or RPR, titers at diagnosis and a diagnosis made in more recent years are associated with serological treatment response…
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Despite guidelines, more than 100 ways PPE doffing process can fail

Gurses AP, et al. Infect Control Hosp Epidemiol. 2018;doi:10.1017/ice.2018.292.
Experts at Johns Hopkins Hospital identified more than 100 ways that health care workers can potentially self-contaminate while doffing personal…
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2-dose regimen of dalbavancin effectively treats osteomyelitis

Rappo U, et al. Open Forum Infect Dis. 2018;doi:10.1093/ofid/ofy331.
A two-dose regimen of dalbavancin — a long-acting lipoglycopeptide antibiotic approved for the treatment of acute bacterial skin and skin…
In the Journals Plus

Koala bites cause wound infections in Australia

Sinclair HA, et al. Emerg Infect Dis. 2018;doi:10.3201/eid2501.171359.
Three people in Queensland, Australia, were infected with a Lonepinella koalarum-like bacteria after being bitten by koalas, researchers reported in…
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