EXPERT SUMMARIES of the top 30 journals in infectious disease
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Osteomyelitis associated with higher rate of fragility fracture at any site

Hsieh E, et al. Clin Infect Dis. 2019;doi:10.1093/cid/ciz077.
Among older men with osteomyelitis, the rate of fragility fracture at any major osteoporotic site is 78% higher compared with those without…
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Correlation between HIV, rectal gonorrhea could help PrEP trial designs

Mullick C, Murray J. J Infect Dis. 2019;doi:10.1093/infdis/jiz037.
Study findings showed a correlation between the incidence of rectal gonorrhea and HIV infection among men who have sex with men who are not using…
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Influenza B associated with similar illness severity, ICU admission rate as influenza A

Korem M, et al. Clin Infect Dis. 2019;doi:10.1093/cid/ciz053.
Patients with influenza B had similar rates of associated disease severity and ICU admission compared with patients with influenza A(H1N1) during two…
In the Journals PlusPerspective

Low testosterone persists after HCV clearance

Chaudhury CS, et al. Clin Infect Dis. 2019;doi:10.1093/cid/ciy965.
Low levels of free testosterone are common among men with chronic hepatitis C infection following SVR and persist after HCV clearance, according to…
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Dalbavancin works as secondary therapy for S. aureus in patients who use drugs

Bryson-Cahn C. et al. Open Forum Infect Dis. 2019;doi:10.1093/ofid/ofz028.
A study evaluating the use of dalbavancin as secondary therapy for serious Staphylococcus aureus infections in people who use drugs found that most…
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Ceftaroline fosamil successfully treats gram-positive infective endocarditis

Destache CJ, et al. Int J Antimicrob Agents 2019;doi:10.0116/j.jijantimicag.2019.01.014.
Researchers found that patients with gram-positive infective endocarditis, including those with infections caused by MRSA, were successfully treated…
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Drug-resistant bacteria prevalent in sinks close to hospital toilets

Buchan BW, Am J Infect Control. 2019;doi.org/10.1016/j.ajic.2018.06.021.
In medical ICU rooms, drug-resistant bacteria are four times more prevalent in sinks located next to toilets than in sinks located farther away…
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UV devices decontaminate CT tables

Cadnum JL, et al. Infect Control Hosp Epidemiol. 2019;doi:10.1017/ice.2018.296.
Study findings showed that UV devices can capably reduce pathogens on CT patient tables, and researchers said the devices “could provide an…
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Antibiotic-resistant genes found in one of the most remote places on Earth

McCann CM, et al. Environ Int. 2019;doi.org/10.1016/j.envint.2019.01.034
Researchers found antibiotic-resistant genes in Svalbard, a Norwegian archipelago in the Arctic Ocean and one of the most remote places on Earth…
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Flu vaccine was 38% effective last season, 22% effective against H3N2

Neuzil KM, Fitzpatrick MC. Clin Infect Dis. 2019;doi:10.1093/cid/ciz078.
Rolfes MA, et al. Clin Infect Dis. 2019;doi:10.1093/cid/ciz075.
The influenza vaccine was 38% effective overall during the 2017-2018 influenza season in the United States, and 22% effective against the predominant…
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New platform delivers same-day AST data for ‘virtually all’ antibiotics

Flentie K, et al. Sci Rep. 2019;doi.org/10.1038/s41598-018-35916-0.
A new platform for antibiotic susceptibility testing, or AST, “has the potential to revolutionize clinical practice” by rapidly providing…
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Hand hygiene compliance ‘remarkably low’ among EMS providers

Vikke HS, et al. BMJ Emerg Med J. 2019;doi:10.1136/emermed-2018-207872.
Study findings showed that hand hygiene compliance among EMS providers is “remarkably low,” with an “over-reliance” on gloves…
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Oral HIV self-testing kit demonstrates 100% specificity, 99.5% sensitivity

Belete W, et al. PLoS One. 2019;doi:10.1371/journal.pone.0210866.
An oral fluid-based HIV self-testing kit demonstrated high diagnostic performance during a facility-based cross-sectional study in Ethiopia, and…
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Goal to eliminate HCV by 2030 will be ‘narrowly missed’

Heffernan A, et al. Lancet 2019;doi:10.1016/S0140-6736(18)32277-3.
Wiktor S. Lancet. 2019:doi:10.1016/S0140-6736(18)32750-8.
As defined by WHO targets, the goal to eliminate hepatitis C virus globally by 2030 will be “narrowly missed,” but is possible by 2032…
In the Journals Plus

Marijuana use increases risk for lung disease in patients with HIV

Lorenz DR, et al. EClinicalMedicine. 2019;doi.org/10.1016/j.eclinm.2019.01.003.
In patients with HIV, long-term marijuana smoking is associated with lung disease independent of tobacco smoking, according to study findings…
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