EXPERT SUMMARIES of the top 30 journals in infectious disease
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Substance use does not lower adherence to PrEP in MSM

Hoenigl M, et al. Emerg Infect Dis.2018; Dec;24(12); doi:10.3201/eid2412.180400.
Study findings showed that substance use does not affect adherence to HIV pre-exposure prophylaxis, or PrEP, among men who have sex with men or…
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Study shows declining efficacy of prophylactic antibiotics to prevent SSIs following colorectal surgery

Gandra S, et al. Infect Control Hosp Epidemiol. 2018:doi:10.1017/ice.
The efficacy of prophylactic antibiotics in preventing surgical site infections following colorectal surgery has declined, according to results from…
In the Journals PlusPerspective

Salmonella infections declined after NYC required restaurants to post inspection grades

Firestone MJ, et al. Emerg Infect Dis. 2018;doi:10.3201/eid2412.180544.
In New York City, Salmonella infections declined after the city health department mandated that restaurants post inspection letter grades in their…
In the Journals PlusPerspective

National program improves hand hygiene, infection control in Australia

Grayson ML, et al. Lancet Infect Dis. 2018;doi:10.1016/S1473-3099(18)30491-2.
A national initiative implemented 8 years ago in Australia has significantly improved hand hygiene compliance among health care workers and led to a…
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In the Journals Plus

7-day metronidazole ‘better’ than single dose to treat trichomoniasis in women

Kissinger P, et al. Lancet Infect Dis. 2018;doi:10.1016/S1473-3099(18)30423-7.
Results from an open-label, randomized controlled trial showed that a 7-day dose of metronidazole is superior to a single dose of metronidazole for…
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2 strains of bacteria cause nearly all TB cases in China

Liu Q, et al. Nat Ecol Evol. 2018;doi:10.1038/s41559-018-0680-6.
Just two strains of Mycobacterium tuberculosis account for almost all cases of tuberculosis in China, according to study findings published in…
In the Journals PlusPerspective

Three-drug regimen more effective for treatment of lymphatic filariasis

King CL, et al. N Engl J Med. 2018;doi:10.1056/NEJMoa1706854.
A three-drug regimen including ivermectin, diethylcarbamazine and albendazole is more effective for the treatment of lymphatic filariasis than the…
In the Journals Plus

Piperacillin-tazobactam ‘particularly damaging’ to gut microbiota

Pettigrew MM, et al. Clin Infect Dis. 2018;doi:10.1093/cid/ciy936.
Piperacillin-tazobactam is “particularly damaging” to human gut microbiota and its use is associated with a low abundance of potentially…
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Review indicates phage therapy safe, effective against ESKAPE pathogens

Haddad LE, et al. Clin Infect Dis. 2018;doi.org/10.1093/cid/ciy947.
A systematic review of published studies showed that phage therapy is a safe and effective treatment for infections caused by multidrug-resistant…
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Recent incarceration associated with increased risk for HIV, HCV

Stone J, et al. Lancet Infect Dis. 2018;doi.org/10.1016/S1473-3099(18)30469-9.
Recent incarceration is associated with an 81% increased risk for HIV and a 62% increased risk for hepatitis C virus acquisition, according to a…
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Donated catered meal sickens hospital staff after Hurricane Harvey

Marguez L, et al. Infect Control Hosp Epidemiol. 2018;doi:10.1017/ice.2018.272.
A donated catered meal seems to be the cause of a foodborne outbreak of Staphylococcus aureus that sickened dozens of staff members last year at a…
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4-month regimen effective in treating less severe TB cases

Imperial MZ, et al. Nat Med. 2018;doi:10.1038/s41591-018-0224-2.
A new analysis of three pivotal tuberculosis trials showed that a shorter treatment regimen — 4 months instead of 6 — is effective in…
In the Journals Plus

UK pay-for-performance program reduced antibiotic prescribing

Balinskaite V, et al. Clin Infect Dis. 2018;doi.org/10.1093/cid/ciy902.
Balinskaite V, et al. Clin Infect Dis. 2018;doi.org/10.1093/cid/ciy904.
The introduction of financial incentives for health care providers to improve the quality of prescribing led to a significant reduction in total and…
In the Journals Plus

Not just flu: ‘Epidemic calendar’ shows seasonality of 69 infectious diseases

Martinez ME. PLOS Pathog. 2018;doi:10.1371/journal.ppat.1007327.
Influenza is not the only infectious disease with a season. Analyzing published data, Micaela E. Martinez, PhD, assistant professor of environmental…
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