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In the Journals Plus

Increase in pertussis linked to nonmedical vaccine exemptions, waning immunity

Aloe C, et al. Proc Natl Acad Sci USA. 2017;doi:10.1073/pnas.1700240114.
Data from five U.S. states with a high incidence rate of pertussis revealed geospatial links between nonmedical vaccine exemptions among…
In the Journals Plus

Washington, D.C., facilities demonstrated 5% CRE prevalence

Reuben J, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.110.
Roughly 5% of all inpatients in Washington, D.C. health care facilities tested positive for carbapenem-resistant Enterobacteriaceae, according to
In the Journals Plus

Flublok Quadrivalent provides better protection than IIV4

Dunkle LM, et al. N Engl J Med. 2017;doi:10.1056/NEJMoa1608862.
Flublok Quadrivalent was 30% more effective in preventing influenza than an egg-derived inactivated quadrivalent influenza vaccine, according to…
In the Journals Plus

Study indicates potential link between influenza during pregnancy and autism

Mahic M, et al. mSphere. 2017;doi:10.1128/mSphere.00159-17.
Although researchers found no evidence that maternal influenza alone was associated with autism spectrum disorder among children, they did observe a…
In the Journals Plus

ID team increases survival of patients with severe sepsis/septic shock

Viale P, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix 548.
A designated team of infectious disease specialists treating severe sepsis or septic shock can improve a patient’s chance of survival…
In the Journals Plus

Financial incentives increase viral suppression in HIV patients

El-Sadr WM, et al. JAMA Intern Med. 2017;doi:10.1001/jamainternmed.2017.2158.
Gift cards used as financial incentives significantly increased viral suppression and continuity in care among patients with HIV, according to a…
In the Journals Plus

HAIs caused by gram-negative bacteria, MRSA increase mortality risk

Nelson RE, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.83.
Data from more than 100 hospitals affiliated with the U. S. Department of Veterans Affairs showed that health care-associated infections due to…
In the Journals Plus

Electronic HCV screening intervention improves testing, linkage to care in baby boomers

Castrejon M, et al. Open Forum Infect Dis. 2017;doi:10.1093/ofid/ofx109.
An electronic health record clinical decision support tool significantly increased hepatitis C virus screening, as well as follow-up testing and
In the Journals Plus

Study findings challenge recommendations for defining recurrent CDI, reinfection

Durovic A, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.119.
Researchers have suggested that extending the currently recommended 8-week cutoff period that distinguishes recurrent Clostridium difficile
In the Journals Plus

Beta-lactam testing in antimicrobial stewardship increases use of preferred antibiotics

Leis JA, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix512.
Using beta-lactam allergy skin testing in antimicrobial stewardship programs significantly increased the use of preferred therapies without
In the Journals Plus

German hand hygiene campaign nearly doubles hand rub use in hospitals

Wetzker W, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.71.
The use of alcohol-based hand rub has nearly doubled in some German hospitals thanks to a national hand hygiene campaign, study data showed.
In the Journals PlusPerspective

CD4+ T cells rebound in HIV patients after chemotherapy

Henrich TJ, et al. J Infect Dis. 2017;doi:10.1093/infdis/jix265.
Despite a temporary — and in some cases “profound” — reduction in CD4+ T cells that were capable of harboring HIV, CD4+ T
In the Journals Plus

Rapid tests for respiratory viruses show high specificity, wide range of sensitivity

Bruning A, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix461.
The sensitivity of rapid tests for detecting respiratory viruses varied widely but showed high specificity, according to a recently published
In the Journals Plus

Antimicrobial stewardship paired with allergy testing increases appropriate therapies

Trubiano JA, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix244.
A program in Australia that integrated antibiotic allergy testing with antimicrobial stewardship significantly improved antibiotic use and
In the Journals PlusPerspective

‘Tweak’ in order set increases HCV screening among patients with HIV

Wurcel AG, et al. Open Forum Infect Dis. 2017;doi:10.1093/ofid/ofx098.
Adding hepatitis C virus screening to an automated order set for patients with HIV greatly increased hepatitis testing at a Massachusetts clinic…
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Depression prevalent in patients with outward signs of lymphatic filariasis

Obindo J, et al. PLoS Negl Trop Dis. 2017;doi:10.1371/journal.pntd.0005567.
Around 20% of patients with obvious physical symptoms of lymphatic filariasis met the criteria for depression in a small study in central Nigeria…
In the Journals PlusPerspective

HIV may prompt progression of HPV infection to cervical precancer

Whitham HK, et al. Cancer Epidemiol Biomarkers Prev. 2017;doi:10.1158/1055-9965.EPI-16-0700.
HPV infection appeared more likely to progress to cervical precancer in women with HIV, according to an analysis from multiple cohorts in Senegal…
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Investigational HCV regimen shows promise in two phase 3 trials

Bourliére M, et al. N Engl J Med. 2017;doi:10.1056/NEJMoa1613512.
An investigational fixed-dose combination regimen containing Sovaldi, velpatasvir and voxilaprevir for the treatment of hepatitis C virus resulted in…
In the Journals Plus

South African men and women, MSM with HIV at increased risk for Kaposi sarcoma

Bohlius J, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix480.
South African men and women with HIV, as well as HIVpositive men who have sex with men on several continents, remained at increased risk for
In the Journals Plus

Malaria drug improves efficacy of glioblastoma treatment

Mulcahy Levy JM, et al. Elife. 2017;doi:10.7553/eLife.19671.
A treatment regimen that included the inexpensive anti-malaria drug chloroquine dramatically improved survival and quality of life for three patients…
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