EXPERT SUMMARIES of the top 30 journals in infectious disease
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IDSA withholds support for international sepsis guidelines

Gilbert DN, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix997.
The Infectious Diseases Society of America has released a position paper explaining why the organization decided not to endorse the 2016 Surviving…
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Researchers track spread of MRSA in England

Coll F, et al. Sci Transl Med. 2017;doi:10.1126/scitranslmed.aak9745.
A longitudinal genomic and epidemiological study in the United Kingdom found that community- and hospital-associated MRSA isolates were both…
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Multimorbidity increasing among patients with HIV

Wong C, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix998.
The prevalence of multimorbidity rose from 8.2% to 22.4% in the United States between 2000 and 2009 among people living with HIV who received…
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HIV vaccine fails to suppress viral load, affect reservoir

Michael NL. Sci Transl Med. 2017;doi:10.1126/scitranslmed.aaq0810.
Sneller MC, et al. Sci Transl Med. 2017;doi:10.1126/scitranslmed.aan8848.
An experimental therapeutic HIV vaccine regimen did not suppress the virus in patients whose ART was paused in a study testing the vaccine’s…
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More California hospitals implement CDC core antimicrobial stewardship measures under state law

Rizzo K, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.218.
The proportion of hospitals in California following all seven of the CDC’s core elements of antimicrobial stewardship programs, or ASPs, rose…
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States that relax Medicaid restrictions see increase in HCV treatment

Kapadia S, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix1062.
State Medicaid programs that relaxed their treatment eligibility requirements for patients with hepatitis C virus demonstrated significantly
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One dose of pneumococcal vaccine plus booster effective

Goldblatt D, et al. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30654-0.
O’Brien KL. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30684-9.
A single dose plus a booster of the 13-valent pneumococcal conjugate vaccine was equal or superior to the current two-dose plus booster schedule for…
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Researchers: WHO HIV guidelines miss patients with low-level viremia

Castagna A, Galli L. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30680-1.
Hermans LE, et al. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30681-3.
Under current WHO HIV guidelines, many patients in lower income countries fall below the threshold for virologic failure but nevertheless face…
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Older antiretroviral regimens raise diabetes risk in HIV-positive adults

Samad F, et al. BMJ Open Diabetes Res Care. 2017;doi:10.1136/bmjdrc-2017-000457.
HIV-positive adults who initiated older formulations of antiretroviral therapy are more likely to develop type 2 diabetes than patients who initiated…
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Many health care workers do not know correct influenza precautions

O’Neil CA, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.232.
In a small survey conducted at a St. Louis hospital, many health care personnel could not describe the correct transmission-based precautions for…
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Water cultures more sensitive than swab cultures to detect Legionella

Decker BK, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.235.
Water cultures are significantly more sensitive than swab cultures in detecting Legionella pneumophila, according to a comparison of the two…
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SHEA, CDC release guidance for epidemiologists in outbreaks

Banach DB, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.212.
The Society for Healthcare Epidemiology of America and the CDC have published guidance for health care epidemiologists on preparing for and…
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C. difficile on the rise in the community

Reveles KR, et al. Am J Infect Control. 2017;doi:10.1016/j.ajic.2017.09.020.
Researchers observed a shift from health care facility-onset Clostridium difficile infections to community-acquired disease over a 12-year period…
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Bivalent norovirus vaccine elicits immune response up to 1 year

Leroux-Roels G, et al. J Infect Dis. 2017;doi:10.1093/infdis/jix572.
In a recent phase 2 trial, several different formulations of a bivalent norovirus vaccine candidate were well-tolerated and induced immune responses…
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Prolonged beta-lactam antibiotics reduce mortality in sepsis

Vardakas KZ, et al. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30615-1.
Paul M, Theuretzbacher U. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30614-X.
Prolonged intravenous infusion of antipseudomonal beta-lactam antibiotics was linked with significantly lower all-cause mortality in patients with

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