EXPERT SUMMARIES of the top 30 journals in infectious disease
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In the Journals Plus

Study finds nearly 25% of antibiotics are unnecessarily prescribed

Chua KP, et al. BMJ. 2019;doi.org/10.1136/bmj.k5092.
In a recent study examining outpatient antibiotic prescriptions filled by privately insured patients, researchers found that of the 40% of patients…
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Only 1 in 10 patients filled ART prescription after hospital discharge

Antoniou T, et al. Open Forum Infect Dis. 2019;doi:10.1093/ofid/ofz009.
Approximately 90% of socially vulnerable patients with HIV did not fill their prescriptions for ART within 7 days of being discharged from a…
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Social intervention in Brazil increases rate of TB cure by 7.6%

Oliosi JGN, et al. Lancet Glob Health. 2019;doi:10.1016/S2214-109X(18)30478-9.
The Bolsa Familia Programme — a conditional cash transfer program in Brazil — directly affects tuberculosis treatment outcomes…
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Beta-lactam/daptomycin combo does not reduce mortality rates in patients with MSSA bacteremia

Grillo S, at al. Clin Infect Dis. 2018; doi.org/10.1093/cid/ciz018.
The combination of a beta-lactam and daptomycin did not improve outcomes in patients with methicillin-susceptible Staphylococcus aureus, or MSSA…
In the Journals Plus

No differences in CDI-related complications between toxin-positive and NAAT-positive-only CDI

Guh AY, et al. Clin Infect Dis. 2018; doi.org/10.1093/cid/ciz009.
Toxin-positive Clostridioides difficile infection, or CDI, tended to be more severe than CDI that was detected through nucleic acid amplification…
In the Journals

Malaria vaccine candidate PAMVAC passes test in humans

Neilsen MA, et al. Clin Infect Dis. 2019;doi:10.1093/cid/ciy1140.
A recent phase 1 clinical trial of the malaria vaccine candidate PAMVAC, designed to protect against pregnancy-associated malaria, or PAM, found that…
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HAdV-7d outbreak underscores need to consider adenoviruses as cause of respiratory illness

Killerby M, et al. Open Forum Infect Dis. 2019;doi:10.1093/ofid/ofz017.
Researchers reporting on a deadly outbreak of human adenovirus type 7d, or HAdV-7d, said clinicians and public health authorities should consider…
In the Journals PlusPerspective

Mortality 6 times higher in CP-CRE carriers subsequently infected with a different genotype

Chen WK, et al. Open Forum Infect Dis. 2019;doi:10.1093/ofid/ofz006.
Researchers found that patients colonized with carbapenem-producing carbapenem-resistant Enterobacteriaceae, or CP-CRE, who are subsequently infected…
In the Journals Plus

Combination therapy 88% effective against HIV, leishmaniasis coinfection

Diro E, et al. PLoS Negl Trop Dis. 2019;doi:10.1371/journal.pntd.0006988.
Extended treatment with a combination of AmBisome plus miltefosine is 88% effective in treating patients with HIV and visceral leishmaniasis…
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Treatment de-intensification fails to reduce toxicity, maintain efficacy in HPV-positive oropharyngeal cancer

Gillison MR, et al. The Lancet 2018;doi:10.1016/S0140-6736(18)32779-X.
Mehanna H, et al. The Lancet. 2018;doi:10.1016/S0140-6736(18)32752-1.
Oosthuizen JC, et al. The Lancet. 2018;doi:10.1016/S0140-6736(18)32930-1.
Patients with advanced, HPV-positive
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Dermatologists prescribing more antibiotics following surgical visits

Barbieri JS, et al. JAMA Dermatol. 2019; doi:10.1001/jamadermatol.2018.4944.
Antibiotic prescribing by dermatologists has “substantially decreased” in recent years, mostly due to a drop in prescriptions for acne…
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Imported cases of Lassa fever often missed for days

Kofman A, et al. Emerg Infect Dis. 2019;doi:10.3201/eid2502.180836.
From 1969 to 2016, 33 cases of Lassa fever were diagnosed in travelers from West Africa to nine other countries, according to a new report…
In the Journals PlusPerspective

Shigella shows high resistance to azithromycin, ciprofloxacin

Ingle DJ, et al. Clin Infect Dis. 2019;doi:10.1093/cid/ciz005.
More than half of tested Shigella isolates obtained from men who have sex with men, or MSM, in an Australian state demonstrated resistance to…
In the Journals PlusPerspective

Study: 14% of transgender women, 3% of transgender men have HIV

Becasen JS, et al. Am J Public Health. 2018;doi:10.2105/AJPH.2018.304727.
Based on a systematic review and meta-analysis of available data, researchers calculated that around 14% of transgender women and 3% of transgender…
In the Journals Plus

26% of black MSM in PrEP trial diagnosed with STI during follow-up

Hightow-Weidman L, et al. Clin Infect Dis. 2019;doi:10.1093/cid/ciy1141.
More than 26% of black men who have sex with men, or MSM, who were enrolled in a pre-exposure prophylaxis, or PrEP, trial were diagnosed with an STI…
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