EXPERT SUMMARIES of the top 30 journals in infectious disease
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Mosquitoes become resistant to gene drive that suppresses fertility

Hammond AM, et al. PLoS Genet. 2017;doi:10.1371/journal.pgen.1007039.
Researchers have developed a gene drive that has the potential to reduce disease-transmitting mosquito populations by limiting female fertility…
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Locally tailored public health messages dispel Ebola myths in Sierra Leone

Kinsman J, et al. PLoS Negl Trop Dis. 2017;doi:10.1371/journal.pntd.0005742.
A two-way channel of communication, appointing community leaders as messengers and communication in local dialects were all instrumental in
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HIV quintuples risk for severe influenza

Ho A, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix903.
Patients with HIV receiving care at a hospital in Malawi were nearly three times more likely to have an influenza-like illness and five times more…
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TDF not linked to adverse perinatal outcomes in pregnant Kenyan, Ugandan women with HIV

Heffron R, et al. J Infect Dis. 2017;doi:10.1093/infdis/jix542.
Tenofovir disoproxil fumarate treatment was not linked to adverse perinatal outcomes in pregnant women with HIV in Kenya and Uganda, a prospective…
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Gonorrhea resistance to AZM reaches 5% threshold among Seattle MSM

Barbee LA, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix898.
In Seattle, an increasing number of gonorrhea infections in men who have sex with men have demonstrated reduced susceptibility to azithromycin…
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Latent TB testing, treatment cost-effective for non-US born residents in most cases

Flood J, Barry PM. JAMA Intern Med. 2017;doi:10.1001/jamainternmed.2017.4916.
Tasillo A, et al. JAMA Intern Med. 2017;doi:10.1001/jamainternmed.2017.3941.
Testing and treatment for latent tuberculosis infection are cost-effective among U.S. residents born outside the country except for those with…
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Sexual contacts of patients with M. genitalium at high risk

Slifirski JG, et al. Emerg Infect Dis. 2017;doi:10.3201/eid2311.170998.
Among sexual contacts of patients with Mycoplasma genitalium, nearly half of women at a large Australian STD clinic were also infected, according to…
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Combination oseltamivir therapy for influenza improves viral shedding, but not clinical benefit

Beigel JH, et al. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30476-0.
Ison MG. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30537-6.
Although combination therapy with oseltamivir, amantadine and ribavirin demonstrated significantly increased viral shedding in patients with
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Too few adults with work-related asthma receive pneumococcal vaccine

Dodd KE, et al. Am J Prev Med. 2017;doi:10.1016/j.amepre.2017.07.022.
Slightly more than half of all adults with work-related asthma had received a pneumococcal vaccine less than the Healthy People 2020 target
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ART in Africa bridges health gap between those with, without HIV

Donald KA. Lancet Glob Health. 2017;doi: 10.1016/S2214-109X(17)30384-4.
Thomas R, et al. Lancet Glob Health. 2017;doi:10.1016/S2214-109X(17)30367-4.
The expansion of ART for HIV infection has helped reduce disparities in health-related quality of life between HIV-positive and HIV-negative…
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Maternal Tdap vaccination prevents whooping cough in newborns

Skoff TH, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix724.
Administering the tetanus-diphtheria-acellular pertussis — or Tdap — vaccine to pregnant women during the third trimester is around 78%…
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Certified nursing assistants often fail to change gloves in long-term care facility

Burdsall DP, et al. Am J Infect Control. 2017;doi:10.1016/j.ajic.2017.02.017.
Certified nursing assistants frequently failed to change their gloves when moving between patients or after touching contaminated surfaces, possibly…
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Virus-specific T cells attack infections after hematopoietic stem cell transplantation

Tzannou I, et al. J Clin Oncol. 2017;doi:10.1200/JCO.2017.73.0655.
An “off-the-shelf” approach using virus-directed virus-specific T cells safely and effectively treated patients with severe viral…
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Antibiotic use, C. difficile increase under electronic sepsis protocol

Hiensch R, et al. Am J Infect Control. 2017;doi:10.1016/j.ajic.2017.04.005.
The implementation of an electronic sepsis protocol coincided with an increase of Clostridium difficile infections and greater use of broad-spectrum
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MRSA, VRE present in hospital food, more studies on infection needed

Kwon JH, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.207.
MRSA and vancomycin-resistant Enterococci can be present in hospital food, although patient infection with either may be uncommon, according to…
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