Infectious Disease News scans the TOP 30 JOURNALS to bring you the most important articles published in your field.
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New drug trials for hospital-acquired pneumonia cost $89,600 per patient

Stergiopoulos S, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix726.
Phase 3 clinical trials of new drugs for hospital-acquired and ventilator-associated pneumonia cost nearly $90,000 per patient, study data
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Few antibiotic trials convey purpose, efficacy goals to patients

Doshi P, et al. JAMA Intern Med. 2017;doi:10.1001/jamainternmed.2017.3820.  
Patients in randomized clinical trials of antibiotics are rarely informed of the purposes of the studies, researchers said. Protocols for…
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Poor kidney function increases risk for community-acquired infections

Xu H, et al. Clin J Am Soc Nep. 2017;doi:10.2215/​CJN.00250117.
Patients with reduced kidney function had an increased risk for developing community-acquired infections — including respiratory, urinary tract…
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Patient empowerment intervention improves hand hygiene

Lastinger A, et al. Am J Infect Control. 2017;doi:10.1016/j.ajic.2017.02.010.
Adult patients and the parents of hospitalized children supported the use of a patient empowerment tool to encourage hand hygiene in physicians…
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Not all symptomatic men will have detectible Zika virus RNA in semen

De Laval F, et al. N Engl J Med. 2017;doi:10.1056/NEJMc1612600.
Findings published in The New England Journal of Medicine suggest that not all men who are symptomatically infected with the Zika virus will have…
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HPV behind nearly 75% of oropharyngeal cancer cases in Canada

Habbous S, et al. CMAJ. 2017;doi:10.1503/cmaj.161379.
The proportion of oropharyngeal cancers associated with HPV in several cancer centers across Canada rose from nearly half to nearly three-quarters…
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Sporicidal, hydrogen peroxide disinfectants effective against multidrug-resistant C. auris

Cadnum JL, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.162.
Researchers investigating the activity of commercial and common household disinfectants against Candida found that sporicidal and improved hydrogen…
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Portable ICU equipment is a potential vector for spreading pathogens

Donskey CJ, et al. Infect Control Hosp Epidemiol. 2017;doi:10.1017/ice.2017.160.
A DNA marker applied to shared portable equipment spread widely throughout an ICU, demonstrating that contaminated equipment is a potential vector…
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HIV drug resistance found in more than half of young children in Africa

Jordan MR, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix698.
Approximately 54% of young children with HIV surveyed in Africa had resistance to one or more antiretroviral drugs, according to recent data. The…
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Enteric fever diagnosed at high rates in Nepal, but rural cases are rare

Andrews JR, et al. J Infect Dis. 2017;doi:10.1093/infdis/jix221.
Although rates of enteric fever diagnosis are high throughout Nepal, culture-confirmed cases were rare in rural areas, according to findings
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Antibiotic use 8 weeks after FMT increases risk for treatment failure

Allegretti JR, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix684.
Antibiotic exposure within 8 weeks of fecal microbiota transplantation, or FMT, was associated with a nearly threefold increased risk for recurrence…
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Community-acquired pneumonia hospitalizes more than 1.5 million patients each year

Ramirez JA, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix647.
Community-acquired pneumonia creates a substantial health care burden in the U.S., forcing the hospitalization of more than 1.5 million adults each…
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Malaria may have been endemic in the Mediterranean since the Roman period

Viganó C, et al. Am J Phys Anthropol. 2017;doi:10.1002/ajpa.23278.
Historical records indicate that malaria became endemic in the Mediterranean during the Middle Ages and remained so until the 1950s, when strong…
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Empirical antibiotics do not reduce mortality in patients with CAUTI

Babich T, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix680.  
Empirical antibiotic treatment did not improve survival of patients with catheter-associated urinary tract infection at an Israeli hospital…
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Despite falling MRSA hospitalizations, serious MRSA-related infections persist

Klein EY, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix640.
Despite an overall decline in methicillin-resistant Staphylococcus aureus infections, hospitalizations from serious, invasive MRSA-related…
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