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Treatment may prevent progressive brain injury in patients with HIV

November 17, 2017

Patients with HIV may experience changes in cognition and brain structure soon after seroconversion, but effective treatment can prevent or minimize progressive brain injury, recent study findings suggest.

“The introduction of combination antiretroviral therapy (cART) has transformed HIV from a fatal disease to a chronic condition,” D. Louis Collins, PhD, professor of biomedical engineering and neurology and neurosurgery at McGill University in Montreal, and colleagues wrote in JAMA Neurology. “However, HIV-associated neurocognitive disorders (HAND) are still prevalent, affecting up to 40% of HIV-positive individuals despite effective viral suppression. The possible cause of this mild brain dysfunction that limits quality of life remains unclear.”

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