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Treatment may prevent progressive brain injury in patients with HIV

November 17, 2017

Patients with HIV may experience changes in cognition and brain structure soon after seroconversion, but effective treatment can prevent or minimize progressive brain injury, recent study findings suggest.

“The introduction of combination antiretroviral therapy (cART) has transformed HIV from a fatal disease to a chronic condition,” D. Louis Collins, PhD, professor of biomedical engineering and neurology and neurosurgery at McGill University in Montreal, and colleagues wrote in JAMA Neurology. “However, HIV-associated neurocognitive disorders (HAND) are still prevalent, affecting up to 40% of HIV-positive individuals despite effective viral suppression. The possible cause of this mild brain dysfunction that limits quality of life remains unclear.”

In the Journals Plus

Long-term data do not support raltegravir as second-line HIV therapy

November 15, 2017
A second-line HIV regimen containing the integrase inhibitor raltegravir failed to meet its primary endpoint of noninferiority against standard second-line treatment…
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DAAs produce cure rates in HCV/HIV co-infection similar to monoinfection

November 13, 2017
Using direct-acting antiviral therapies demonstrated similarly high rates of sustained virologic response for hepatitis C virus infection in patients with and without…
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San Francisco reports record low number of new HIV diagnoses

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Researchers in San Francisco identified 223 new HIV diagnoses in 2016 — the lowest ever recorded in the city. Meanwhile, treatment coverage and viral suppression…
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HIV/AIDS 1 Hour Update For Florida Health Professionals

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This is a 1 hour activity designed for home study by healthcare clinicians. Specifically, it meets the 1 hour HIV/AIDS…
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In the Journals Plus

Schistosomiasis increases HIV risk in African women

November 1, 2017
A half-century of progress fighting schistosomiasis in China is being jeopardized by land-use patterns and landscape…
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