Steatohepatitis/Metabolic Liver Disease

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Proton density fat fraction accurately classifies hepatic changes in NASH

September 18, 2017

Proton density fat fraction, or PDFF, estimated by magnetic resonance imaging scanners of different field strength and at different sites accurately classified changes in hepatic steatosis compared with histologic analysis of biopsies, according to a recently published study.

“We found that PDFF correlates well with histologic hepatic steatosis grade cross-sectionally, and that change in PDFF correlates well with change in histologic hepatic steatosis grade longitudinally,” Michael S. Middleton, MD, PhD, from the University of California, San Diego, and colleagues wrote. “Although we did not perform a direct comparison of [controlled attenuation parameter (CAP)] and PDFF, the accuracy of MRI to estimate PDFF has been reported to be higher than that of CAP, using histology as reference standard.”

In the Journals

Chronic kidney disease risk increases with NAFLD severity

September 6, 2017
The risk for chronic kidney disease increased as nonalcoholic fatty liver disease progressed in severity, according to a recently published study. “Our findings…
In the Journals

Sleep deprivation linked to NAFLD, serum aminotransferase levels

September 5, 2017
Shorter sleep durations were correlated with abnormal serum alanine aminotransferase levels and development of nonalcoholic fatty liver disease among U.S. adults…
In the Journals

Anti-copper therapy safe for pregnant patients with Wilson’s disease

September 1, 2017
Women with Wilson’s disease who received anti-copper therapy during pregnancy had fewer spontaneous abortions compared with those who did not receive therapy…
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CME Video

Case Challenges in Pediatric Fatty Liver: What to Look For and When to Refer

This activity is supported by an educational grant from Synageva BioPharma Corp.

Non-alcoholic fatty liver disease (NAFLD) is characterized by excess fat deposition in the liver due to causes other…
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GI Bookshelf

Chapter 10: Colonic Stenting

From Core Concepts in Colonoscopy
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Resource Centers
International Liver Congress

International Liver Congress

Meeting News

VIDEO: Hispanic patients at higher risk for developing fatty liver disease

March 21, 2017
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