Hepatitis C highlights from The Liver Meeting 2018

December 12, 2018
This year at The Liver Meeting, data presented on hepatitis C treatment highlighted continued significantly positive outcomes from direct-acting…
In the Journals

Sofosbuvir safe for patients with cancer, linked to NHL remission

December 12, 2018
Sofosbuvir-based therapy was safe and effective in as short as 8 weeks for treating hepatitis C in patients with cancer and may induce remission of…

Integral Molecular receives $1.4 million from NIH for NASH therapeutic

December 11, 2018
Integral Molecular received $1.4 million from the National Institutes of Health to develop its lead antibodies against cannabinoid receptor 1 for…
In the Journals

Anticoagulants improve outcomes in cirrhosis-related portal vein thrombosis

December 11, 2018
Anticoagulant treatment safely and effectively led to partial or complete recanalization of the portal venous system in more than half of patients…
FDA News

FDA grants orphan drug designation to M7824 for biliary tract cancer

December 11, 2018
The FDA granted orphan drug designation to M7824 for the treatment of biliary tract cancer. This is the first regulatory designation for M7824…
Feature

How US-Canada-Mexico trade deal could impact drug prices, research

December 11, 2018
The United States-Mexico-Canada Agreement keeps drug prices high but could potentially spur new research opportunities, a pharmaceutical expert told…
FDA News

FDA clears app for patients in treatment for opioid use disorder

December 10, 2018
The FDA has approved a mobile medical app that could increase the time a patient participates in an outpatient treatment program for opioid use…
In the Journals

Sorafenib with TACE improves response to HCC, not overall survival

December 10, 2018
Sorafenib combined with conventional transarterial chemoembolization for patients with advanced hepatocellular carcinoma improved time to…
In the Journals

Liver preservation technique improves 5-year graft survival

December 10, 2018
Donation after circulatory death livers treated with hypothermic oxygenated perfusion had similar 5-year posttransplant outcomes as donation after…

Antios Therapeutics raises $25 million for potential HBV curative therapy

December 8, 2018
Antios Therapeutics completed a $25 million oversubscribed Series A financing to develop ATI-2173, an oral drug candidate for treating patients with…
In the Journals

Cirrhosis, PSC predict mortality risk in autoimmune hepatitis

December 7, 2018
Patients with autoimmune hepatitis without cirrhosis had a similar survival rate as the general population, whereas those with cirrhosis had…

Elafibranor for PBC reduces alkaline phosphatase, pruritus

December 6, 2018
Elafibranor met its phase 2 primary endpoint of reducing alkaline phosphatase after 12 weeks of treatment in patients with primary biliary…
In the Journals

MELD score change during HBV therapy reduces mortality risk

December 6, 2018
On-treatment improvement of MELD scores correlated with reduced risk for all-cause mortality and hepatic events among patients with chronic hepatitis…
In the Journals

Treatment for HCV regardless of SVR lowers risk for CVD events

December 5, 2018
Treatment with either pegylated interferon with ribavirin or direct-acting antivirals for hepatitis C correlated with a significantly lower risk for…

ProSciento forms NASH Roundtable of experts to guide clinical research

December 5, 2018
ProSciento organized and funded the formation of the “NASH Roundtable,” a collaborative forum of leading academic and clinical…
In the Journals PlusPerspective

Liver disease common in children with type 2 diabetes

December 5, 2018
An analysis of data from a small cohort of children with type 2 diabetes and nonalcoholic fatty liver disease, or NAFLD, suggests that nonalcoholic…

Liver transplantation highlights from The Liver Meeting 2018

December 4, 2018
This year at The Liver Meeting, data presented on liver transplantation focused on comorbid complications, such as alcohol misuse and obesity, and…
In the JournalsPerspective

AMA: Only 15% of physicians practice telemedicine

December 4, 2018
Only 15.4% of physicians worked in practices that utilized telemedicine for patient interactions, such as diagnosing or treating patients, managing…
In the Journals

Mavyret achieves 97% SVR in real-world cohort of patients with HCV

December 3, 2018
Mavyret demonstrated 97% sustained virologic response in a large, real-world cohort of patients with hepatitis C over an 8-week course and extended…

Medicines Patent Pool signs license for generic production of Mavyret

December 3, 2018
The Medicines Patent Pool signed a royalty-free license agreement with AbbVie to enable quality-assured manufacturers to develop and sell generic…