September 19, 2017
“As there exists a regional variation in the prevalence of HCV and health care practices, studying the clinical profile of HCV in different parts of the world assumes significance for the development of strategies to prevent and treat HCV infection,” the researchers wrote. “This information can have a great impact on making and/or reshaping policies on screening and curing the current infections as well as preventing new ones.”
At initial diagnosis, most patients had chronic HCV (55.8%) and many had cirrhosis (44.2%). Among the patients with cirrhosis, 12.9% had decompensation and 5.4% had hepatocellular carcinoma. Factors associated with cirrhosis and HCC at presentation included male sex, age older than 40 years and rural residence (P < .05). Most patients who presented with cirrhosis had a family history of HCV and received a diagnosis during family screening.