In the Journals

ACG releases clinical guideline for hereditary hemochromatosis

July 24, 2019
The American College of Gastroenterology released a new clinical guideline for the screening, diagnosis and treatment of hereditary hemochromatosis…

Feature

AASLD Foundation presents grants to young hepatologists for research, careers

July 18, 2019
The American Association for the Study of Liver Diseases Foundation has granted $3.42 million in research and career development awards to 29…

Meeting News

Gene variants responsible for excess liver iron

June 18, 2019
Researchers found that excess liver iron was most likely a systemic problem related to genes rather than an organ-related problem, according to a…

CAMP4, Alnylam partner to identify rare liver disease genetic targets

January 24, 2019
CAMP4 Therapeutics and Alnylam Pharmaceuticals announced a collaboration designed to identify new medication targets of an undisclosed rare liver…

Special Issue Article

Wilson's Disease: A Review for the General Pediatrician

Pediatric Annals, November 2018, Volume 47 Issue 11
Wilson's disease, also known as hepatolenticular degeneration, is an autosomal recessive genetic disorder due to a mutation of the ATP7B gene…

Meeting News

Healio to provide live coverage of The Liver Meeting 2017

October 21, 2017
WASHINGTON — Beginning Friday, October 20, Healio Gastroenterology and Liver Disease will provide live coverage from the The Liver Meeting…

Meeting News

Kanuma improves liver markers in patients with lysosomal acid lipase deficiency

December 6, 2016
BOSTON — Kanuma improved various liver markers, as well as reduced liver fibrosis and cirrhosis, in children and adults with lysosomal acid…

Arrowhead discontinues multiple drug candidates for liver disease

December 1, 2016
Arrowhead Pharmaceuticals announced it has discontinued development of three drugs currently being investigated in clinical trials for the treatment…

FDA News

FDA grants rare pediatric disease label to investigational drug for NPC

November 30, 2016
The FDA has issued rare pediatric disease designation to an investigational gene therapy product candidate for the treatment of children with…

FDA News

FDA grants orphan drug designation to PRX-OTC for rare liver disease

November 28, 2016
The FDA granted PhaseRx Inc. orphan drug designation for PRX-OTC for the treatment of the rare liver disease ornithine transcarbamylase deficiency

FDA News

FDA grants orphan drug designation to BTT1023 for PSC

August 29, 2016
The FDA granted Biotie Therapies Corporation orphan drug designation for BTT1023 to treat primary sclerosing cholangitis, according to a press…

In the Journals

Somatuline Depot injection reduces liver volume in polycystic liver disease

January 28, 2016
In the LOCKCYST I clinical trial, a low dose of Somatuline Depot injection for the treatment of polycystic liver disease was found to be safe and…

In the Journals

Somatostatin analogues found to improve HRQL in patients with polycystic liver disease

July 22, 2015
In an analysis of placebo-controlled clinical trials, somatostatin analogues improved health-related quality of life among patients with polycystic…

FDA News

FDA grants ARC-AAT orphan drug status to treat liver disease

June 11, 2015
ARC-AAT has been granted orphan drug designation by the FDA for the treatment of liver disease associated with alpha-1 antitrypsin deficiency…

In the Journals

MRI shows limited diagnostic efficacy for liver iron overload

January 8, 2015
MRI may be accurate in ruling out hepatic iron overload but not accurate enough to provide a definite diagnosis, according to recent study data. …

Industry News

Hepatology group urges UK’s health service to combat rise in liver disease

March 26, 2014
Members of the All-Party Parliamentary Hepatology Group have asked the National Health Service in the United Kingdom to show more concern about the…

In the Journals

Bariatric surgery yields genetic changes among patients with NAFLD

August 6, 2013
Patients with nonalcoholic fatty liver disease who undergo bariatric surgery may experience DNA-altering effects that can reverse their disease…

In the Journals

Post-liver transplant survival rates high among pediatric, adult patients with lethal genetic syndromes

May 10, 2013
Patients who underwent liver transplantation to treat lethal genetic syndromes experienced high rates of survival, while factors such as age and…

Meeting News Coverage

Gene variants linked to steatosis, fibrosis, steatohepatitis

April 25, 2013
Variants in the PNPLA3, GCKR, TRIB1 and PPP1R3B genes are associated with histological factors of nonalcoholic fatty liver disease, according to data…

In the Journals

Diabetes may be associated with liver fibrosis in patients with hemochromatosis

July 25, 2012
An association may exist between the presence of diabetes and severe liver fibrosis in patients with hereditary hemochromatosis, according to recent…