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Kanuma improves liver markers in patients with lysosomal acid lipase deficiency

Kanuma improves liver markers in patients with lysosomal acid lipase deficiency
December 6, 2016

BOSTON — Kanuma improved various liver markers, as well as reduced liver fibrosis and cirrhosis, in children and adults with lysosomal acid lipase deficiency, according to long-term results of the phase 3 ARISE clinical trial presented at The Liver Meeting.

“The drug is very effective in both reducing inflammation in the liver and improving dyslipidemia which we expect to be translated to reduced cardiovascular risk. These improvements persisted over a period of 76 weeks so there are lasting effects,” Barbara K. Burton, MD, professor of pediatrics, Northwestern University Feinberg School of Medicine, and attending physician at the Ann and Robert H. Lurie Children’s Hospital of Chicago, told Healio.com/Hepatology.

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