Drug Metabolism/Pharmacology

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Noninvasive test monitors fibrosis in methotrexate-treated psoriasis

August 23, 2017

The novel, noninvasive NASH FibroSure test may have utility in monitoring fibrosis risk in patients treated for psoriasis with methotrexate, according to recent findings.

In the current single-center, retrospective study, researchers evaluated 129 patients for hepatic fibrosis and hepatotoxic effects of methotrexate between Jan. 1, 2007, and Dec. 31, 2013.

In the Journals

Ibuprofen most frequent drug-induced liver injury agent in Spain

August 10, 2017
Ibuprofen is one of the most frequent causative agents listed in the Spanish and Latin-American registries of the Drug-Induced Liver Injury Network, according to a…
In the Journals

Drug-induced liver injury more severe in African-Americans than whites

August 7, 2017
Comparative data from the Drug-Induced Liver Injury Network Prospective Study showed that the most common drug-induced liver injury causative agents differ between…

FDA grants orphan drug designation for primary hyperoxaluria treatment

July 14, 2017
Allena Pharmaceuticals has received an orphan drug designation from the FDA for its investigational product ALLN-177 for the treatment of primary hyperoxaluria and…
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