Hematology/Oncology

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FDA advisory committee split on opinion of adjuvant Sutent for renal cell carcinoma

September 19, 2017

The FDA’s Oncologic Drug Advisory Committee today voted 6-6 on whether the risk-benefit profile of sunitinib malate is acceptable for the adjuvant treatment of patients with a high-risk for recurrent renal cell carcinoma following nephrectomy.

The committee considered data from the S-TRAC trial, which randomly assigned patients at high risk for recurrent renal cell carcinoma following nephrectomy to 1 year of sunitinib (Sutent, Pfizer Oncology; n = 309) or placebo (n = 306). Patients assigned sunitinib received 50-mg doses for 4 weeks following by 2 weeks off, and the dose could be reduced to 37.5 mg.

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Hot Topics in Metastatic Breast Cancer Management: Clinical Advances with CDK4/6 Inhibitors

This activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.

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European Society for Medical Oncology Congress

European Society for Medical Oncology Congress

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Immune Checkpoint Inhibitors for Advanced Melanoma: Clinical Updates and Multidisciplinary Strategies

This activity is supported by an educational grant from Bristol-Myers Squibb.

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