Hematology/Oncology

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HIV infection associated with subsequent squamous cell carcinoma risk

July 26, 2017

Non-Hispanic white patients with HIV and a history of nonmelanoma skin cancer had a higher risk for subsequent new primary squamous cell carcinoma, which was particularly associated with lower CD4 counts and higher viral loads, when compared with patients without HIV, according to recently published study results.

Researchers conducted a cohort study of 455 patients with HIV (mean age, 52.6 years; 3% women) and 1,945 patients without HIV (mean age, 55.5 years; 8% women) who were diagnosed with at least one nonmelanoma skin cancer (NMSC) between 1996 and 2008 to determine risk for subsequent NMSCs in relation to CD4 count and viral load. NMSC was defined as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC)

FDA News

Eisai submits supplemental new drug application to FDA for Lenvima

July 26, 2017
Eisai submitted a supplemental new drug application to the FDA to seek approval for lenvatinib as a frontline therapy for patients with hepatocellular carcinoma. The…

Physicians cautiously optimistic as they gain knowledge of biosimilars

July 26, 2017
Although research has shown that biosimilars complement the biologic armamentarium for managing chronic diseases, concerns regarding their implementation have caused…
In the Journals Plus

Bone marrow biopsy unnecessary for follicular lymphoma clinical trials

July 26, 2017
Bone marrow biopsy did not change response assessments after treatment among patients enrolled in clinical trials for follicular lymphoma, which suggests mandatory…
In the Journals Plus

Adjuvant ovarian function suppression in young women

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Adjuvant ovarian function suppression with either tamoxifen or exemestane significantly improved the breast cancer–free interval in young women with hormone…
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CME

Polycythemia Vera: Aligning Real World Practices With Current Best Practices

This activity is supported by an independent educational grant from Incyte Corporation.

Ruben A. Mesa, MD, provides practical insights into treating polycythemia vera in this video series. In addition to…
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Video
Meeting News

VIDEO: Adam Brufsky, MD, PhD, discusses results of MONARCH-2, PALOMA-1 trials

June 23, 2017
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Resource Centers
Biosimilars in the US

Biosimilars in the US

CME

Immune Checkpoint Inhibitors for Advanced Bladder Cancer: Applying Clinical Advances and Elucidating Best Practices

This activity is supported by an educational grant from Merck & Co, Inc.

Advances in immunology and the advent of immune checkpoint blockade inhibition for advanced bladder cancer are poised…
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