Feature

CAR T-cell therapy may be effective for colorectal cancer

July 13, 2018
Chimeric antigen receptor T-cell therapy may be an effective treatment strategy for colorectal cancer, according to study results. Adam
FDA News

FDA approves Opdivo-Yervoy combination for subset of patients with metastatic colorectal cancer

July 11, 2018
The FDA granted accelerated approval to the combination of nivolumab and low-dose ipilimumab for treatment of microsatellite instability-high or…
In the Journals Plus

Certain patients with melanoma may benefit from anti-PD-1 treatment after progression

July 8, 2018
Patients with melanoma who continued treatment with anti-PD-1 therapy following disease progression demonstrated decreased tumor burden and prolonged…
In the Journals Plus

Nivolumab shows antitumor activity in nasopharyngeal carcinoma

July 6, 2018
Nivolumab showed promising clinical activity among patients with pretreated recurrent or metastatic nasopharyngeal carcinoma, according to data…
Feature

Fratricide-resistant CAR T-cell therapy may have utility in acute lymphoblastic leukemia

July 5, 2018
Patients with relapsed or refractory acute lymphoblastic leukemia may benefit from a novel fratricide-resistant chimeric antigen receptor T-cell…
FDA News

FDA grants priority review to Keytruda plus chemotherapy for lung cancer subtype

July 2, 2018
The FDA granted priority review designation to a supplemental biologics license application that seeks approval of pembrolizumab for use in…

Atezolizumab plus chemotherapy improves PFS for triple-negative breast cancer

July 2, 2018
First-line atezolizumab plus nab-paclitaxel improved PFS compared with placebo among patients with metastatic or unresectable locally advanced…
Feature

Survivin may be target for immunotherapies in several malignancies

June 27, 2018
Survivin, an inhibitor of apoptosis protein, may be an attractive target for a variety of immunotherapeutic approaches for cancer, according to study…
Feature

CD40 may be key to activating immune response in pancreatic cancer

June 27, 2018
Researchers at University of Pennsylvania are investigating anti-CD40 antibodies in a number of combinations in pancreatic cancer and other…
In the Journals Plus

Poliovirus shows promise for treatment of advanced glioma

June 26, 2018
An intratumoral infusion of recombinant nonpathogenic polio-rhinovirus chimera appeared safe and prolonged survival among patients with stage IV…