Molecular Oncology

Translating an explosion of knowledge in molecular oncology

HemOnc Today, September 10, 2018
Wafik S. El-Deiry, MD, PhD, FACP
There have been many advances in the molecular analysis of cancer in recent years, with an explosion of knowledge that can be daunting and rapid…

Which is the better use of resources: increasing HPV vaccine uptake or developing new vaccines that protect against all oncogenic HPV strains?

HemOnc Today, September 10, 2018
POINT When we started developing HPV vaccines 15 to 20 years ago, we were targeting cervical cancer. First-generation HPV vaccines covered approximately…
Cover Story

Efficacy data, cost-effectiveness will guide decision to expand HPV vaccination to older adults

HemOnc Today, September 10, 2018
The number of Americans eligible to receive the HPV vaccine could expand dramatically this fall. The HPV 9-valent vaccine, recombinant (Gardasil 9…

Harvard initiative aims to determine why certain patients are ’exceptional responders’

September 6, 2018
A Harvard Medical School project will mine multiple data sources to try to determine why some patients are more likely to have exceptional responses…

ASCO issues ‘more structured guideline’ for metastatic pancreatic cancer

August 30, 2018
ASCO released updated recommendations that incorporate new evidence related to second-line therapy for patients with metastatic pancreatic cancer who…

Guidelines intended to accelerate diagnosis, improve management of von Willebrand disease

August 24, 2018
Several organizations have collaborated to develop clinical practice guidelines for the diagnosis and management of von Willebrand disease. von…
Pharmacology Consult

Urgent action necessary to address opioid drug shortage

HemOnc Today, August 25, 2018
Jai N. Patel, PharmD, BCOP
The frequency of drug shortages in the United States is rapidly increasing. Shortages of opioid drugs — such as injectable hydromorphone…

Natural killer cells as effective as, less toxic than T cells

August 21, 2018
Natural killer cells engineered with chimeric antigen receptors demonstrated comparable efficacy as T cells but appeared less toxic, according to…

Risk-adapted approach may help some children with medulloblastoma avoid radiation, chemotherapy

July 31, 2018
Molecular subtyping may help develop a risk-adapted approach for treating children with medulloblastoma. Giles W. Robinson, MD, assistant…

Trial represents ‘bold move’ for treatment of newly diagnosed myeloma

July 26, 2018
Researchers at The University of Alabama at Birmingham are recruiting for a phase 2 clinical trial designed to offer an innovative treatment approach…