Molecular Oncology

Treatment response in AML: Understanding available molecular diagnostic data

HemOnc Today, April 10, 2019
David F. Claxton, MD; Megan Wheelden, MD
“Doctor, am I in remission?” The honest current answer is often: “It depends what you mean by remission.”
Commentary

Immunotherapy for head and neck cancer an evolving paradigm

HemOnc Today, April 10, 2019
Charu Aggarwal, MD, MPH
The availability and approval of checkpoint inhibitors has transformed the management of metastatic head and neck squamous cell carcinoma. In 2016…
Point/Counter

Is ibrutinib-based therapy the preferred initial treatment for all patients with CLL?

HemOnc Today, April 10, 2019
POINT CLL is the most common leukemia among adults. Standard treatment is combination chemoimmunotherapy with regimens such as chlorambucil plus…
Cover Story

Advances in chronic lymphocytic leukemia suggest progress is ‘visible on the horizon’

HemOnc Today, April 10, 2019
The transition from primarily chemotherapy-based approaches to targeted therapies revolutionized treatment of chronic lymphocytic leukemia, the most…
Feature

BRCA Exchange addresses ‘urgent need’ for data sharing in cancer predisposition research

April 9, 2019
The Global Alliance for Genomics and Health has launched a global public repository that includes data on thousands of inherited variants in the…
Feature

Trial explores T-cell therapy’s role in personalized treatment for lung cancer

April 4, 2019
ATLANTA — In the battle against non-small cell lung cancer, the ability to personalize treatment may be a key to victory, according to Karen
Point/Counter

Will CAR T cells become first-line therapy for hematologic malignancies?

HemOnc Today, March 25, 2019
POINT CAR T cells have already changed the treatment paradigm for recurrent and resistant DLBCL, which, as shown in the SCHOLAR-I study, has a dismal…
Cover Story

New indications may accelerate ‘explosion’ in CAR T-cell therapy, but more education still needed

HemOnc Today, March 25, 2019
Years of research into chimeric antigen receptor T-cell therapy for cancer treatment is finally paying dividends. When Renier J. Brentjens, MD
Feature

Patient feedback can help ensure balance between cancer treatment efficacy, tolerability

March 18, 2019
Researchers have launched a research consortium that they hope will identify efficient methods to incorporate patient-reported outcomes into clinical…
Feature

Biomarker may help better predict outcomes in HPV-positive head, neck cancer

March 15, 2019
Researchers have identified a gene panel that could lead to less intensive treatment for certain patients with HPV-positive oropharyngeal squamous…