EXPERT SUMMARIES of the top 30 journals in hematology & oncology
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Extended red blood cell storage does not increase in-hospital mortality

Cook RJ, et al. Lancet Haematol. 2017;doi:10.1016/S2352-3026(17)30169-2.
Gehrie EA and Tobian AAR. Lancet Haematol. 2017;doi:10.1016/S2352-3026(17)30179-5.
Transfusing red blood cells stored longer than 35 days did not increase risk for in-hospital death compared with fresh blood, according to a…
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Prevalence of secondary cancers underscores need for trial inclusion

Murphy CC, et al. JAMA Oncol. 2017;doi:10.1001/jamaoncol.2017.3605.
A quarter of older adults newly diagnosed with cancer from 2009 to 2013 had a prior cancer history, according to an observational study published in…
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Primary prevention improves colorectal cancer survival over early detection

Doroudi M, et al. Cancer. 2017;doi:10.1002/cncr.31034.
Segnan N and Armaroli P. Cancer. 2017;doi:10.1002/cncr.31032.
Primary prevention of colorectal cancer through the removal of adenomatous polyps led to greater mortality reductions than early detection of the…
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Many cancers associated with modifiable risk factors

Islami F, et al. CA Cancer J Clin. 2017;doi:10.3322/caac.21440.
Cigarette smoking, excess body weight and alcohol intake represented the three most prevalent modifiable risk factors for cancer, according to an…
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Thyroid cancer increases CVD morbidity risk

Pajamaki N, et al. Clin Endocrinol. 2017;doi:10.1111/cen.13519.
Adults treated for differentiated thyroid cancer have an increased risk for cardiovascular disease morbidity compared with those without cancer; and…
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HPV testing more effective than Pap smear for detecting cervical cancer

Schiffman M, et al. J Natl Cancer Inst. 2017;doi: 10.1093/jnci/djx225.
Cotesting women for cervical cancer using a combination of HPV test and Pap smear did not detect cancers that could not be identified by HPV
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Persistent opioid use common after cancer surgery

Lee JS, et al. J Clin Oncol. 2017;doi:10.1200/JCO.2017.74.1363.
New, persistent opioid use is a common health-care related complication among patients with cancer who underwent curative surgery, study data
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PTSD common after cancer diagnosis

Chan CM, et al. Cancer. 2017;doi:10.1002/cncr.30980.
One-fifth of patients with cancer experienced PTSD within several months of diagnosis, according to results of a prospective study published in…
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Long-term differentiated thyroid cancer survival linked to diastolic dysfunction

Klein Hesselink MS, et al. Thyroid. 2017;doi:10.1089/thy.2017.0383.
Long-term survivors of pediatric differentiated thyroid cancer are more likely to have diastolic dysfunction, suggesting early cardiac aging…
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Osimertinib superior to standard first-line treatments for EGFR-mutated lung cancer

Soria J-C, et al. N Engl J Med. 2017;doi:10.1056/NEJMoa1713137.
First-line treatment with osimertinib prolonged PFS compared with standard epidermal growth factor receptor tyrosine kinase inhibitors among patients…
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Radiotherapy shows potential role in treatment of Hodgkin lymphoma subtype

Odei B, et al. Clin Lymphoma Myeloma Leuk. 2017;doi:10.1016/j.clml.2017.09.013.
Radiotherapy prolonged OS among patients with all stages of nodular lymphocytic Hodgkin lymphoma, including those with B-symptoms, according to study…
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Lomustine, bevacizumab fail to improve OS in progressive glioblastoma

Wick W, et al. N Engl J Med. 2017;doi:10.1056/NEJMoa1707358.
The addition of lomustine to bevacizumab failed to confer a survival advantage for the treatment of progressive glioblastoma, according to results of…
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Black women with type 2 diabetes at greater risk for breast cancer subtype

Palmer JR, et al. Cancer Res. 2017:doi:10.1158/0008-5472.CAN-17-1903.
Black women with type 2 diabetes demonstrated a 40% increased risk for ER-negative breast cancer, according to results of a study published in…
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Androgen deprivation therapy does not increase risk for Alzheimer’s disease, dementia

Baik SH, et al. J Clin Oncol. 2017:doi:10.1200/JCO.2017.72.6109.
Older men treated with androgen deprivation therapy for prostate cancer appeared to be at no greater risk for Alzheimer’s disease or dementia…
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Childhood cancer survivors more likely to stay at jobs for health insurance

Kirchoff AC, et al. JAMA Oncol. 2017;doi:10.1001/jamaoncol.2017.3372.
Job lock — the tendency to stay at a job in order to keep employer-provided health insurance — is common among childhood cancer
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