Fox Chase Cancer Center announces appointments

May 26, 2019
Fox Chase Cancer Center announced several faculty appointments and promotions. Michael Hall, MD, has been named chair of the department of…

Mount Sinai thoracic surgeon receives award

May 25, 2019
Raja M. Flores, MD, received New York University’s Distinguished Alumni Service Award, which recognizes his accomplishments and services to…

FDA approves Piqray, first PI3K inhibitor for advanced breast cancer

May 24, 2019
The FDA on Friday approved alpelisib, the first PI3K inhibitor to treat postmenopausal women and men with hormone receptor-positive, HER2-negative…
FDA News

FDA approves Jakafi for acute graft-versus-host disease

May 24, 2019
The FDA approved ruxolitinib for the treatment of steroid-refractory acute graft-versus-host disease among adults and children aged 12 years and…
Meeting NewsVideo

VIDEO: Stool-based colon cancer tests may be effective between scheduled colonoscopies

May 24, 2019
SAN DIEGO — In this exclusive video from Digestive Disease Week, John B. Kisiel, MD, a gastroenterologist at the Mayo Clinic, discusses the…
Meeting NewsVideo

VIDEO: Novel DNA markers accurately detect pancreatic cancer across all stages

May 24, 2019
SAN DIEGO — In this video from Digestive Disease Week, Shounak Majumder, MD, a gastroenterologist at the Mayo Clinic, discusses the results of…
Feature

AI has potential to disrupt and transform cancer care, center director says

May 24, 2019
Translating genomic and big data into clinical tools for physicians and patients with cancer is an enormous challenge that has been enthusiastically…
Trend Watch

UCLA Researchers Awarded $4.6m for Stem Cell Immunotherapy Trial

Cell Therapy Next, May 2019
The California Institute for Regenerative Medicine has awarded a $4.6 million grant for a phase 1 clinical trial of a new modified blood-forming stem…
Clinical Trials Snapshot

Umbilical & Cord Blood (CB) Derived CAR-Engineered NK Cells for B Lymphoid Malignancies

Cell Therapy Next, May 2019
Phase 1/2 dose-escalation trial to determine the safety and efficacy of chimeric antigen receptors (CAR).CD19-CD28-zeta-2A-iCasp9-IL15-transduced…
In Practice

The Handoff: Transferring CAR T Patients Back to the Community Setting

Cell Therapy Next, May 2019
Julio C. Chavez, MD
In this installment of In Practice, Julio C. Chavez, MD, assistant member in the lymphoma section of the department of malignant hematology at…
In the JournalsPerspective

New CAR T-cell Therapy Shows No Severe Toxic Side Effects

Cell Therapy Next, May 2019
A novel version of CAR T-cell therapy has shown no severe toxic side effects in patients with recurrent lymphoma, according to a study published in…
Clinical Trials Snapshot

Intraperitoneal Delivery of Adaptive Natural Killer (NK) Cells (FATE-NK100) With Intraperitoneal Interleukin-2

Cell Therapy Next, May 2019
Phase I trial to determine the maximum tolerated/maximum feasible dose of a single infusion of FATE-NK100 via intra-peritoneal catheter in women with…
Clinical Trials Snapshot

Natural Killer Cells and Bortezomib to Treat Cancer

Cell Therapy Next, May 2019
A phase 1, non-randomized, open-label, dose-escalation interventional study to evaluate the safety and the anti-tumor effects of escalating doses of…
Clinical Trials Snapshot

GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With Neuroblastoma

Cell Therapy Next, May 2019
Phase 1 trial to find the largest effective and safe dose of GD2-CAR NKT cells (GINAKIT cells) and evaluate their effect on the tumor, how long they…
Clinical Trials Snapshot

Cytokine Induced Memory-like NK Cell Adoptive Therapy for Relapsed AML After Allogeneic Hematopoietic Cell Transplant

Cell Therapy Next, May 2019
Phase 1 open-label trial examining the feasibility and safety of combining CIML NK cells with the donor lymphocyte infusion approach to significantly…
Clinical Trials Snapshot

A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications

Cell Therapy Next, May 2019
Phase 1, open label, multinational (EU/US) trial to assess the safety and clinical activity of NKR-2 treatment administered 3 times with a 2-week…
Cover Story

‘A Moment of Marvel’ in Manhattan Brings a Revolution in CAR T-Cell Therapy

Cell Therapy Next, May 2019
When the first flow cytometry analysis was run after a CAR T-cell therapy, showing no evidence of leukemia, Michel Sadelain, MD, PhD, and Isabelle
FDA News

FDA approves tumor-treating fields system for mesothelioma

May 24, 2019
The FDA approved NovoTTF-100L, a tumor-treating fields delivery system, for use in combination with pemetrexed plus platinum-based chemotherapy for…
Feature

Blood test may serve as noninvasive alternative to colonoscopy

May 24, 2019
A study underway in West Virginia is designed to evaluate a novel blood test that may prove a more acceptable alternative for patients unwilling to…
In the Journals

Previous hematologic malignancies increase risk for head and neck cancers

May 23, 2019
Individuals previously diagnosed with a hematologic malignancy appeared at higher risk for developing head and neck cancers, according to results of…