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Kids First Data Resource Center set to ‘unlock potential’ of genomic data in pediatric cancer

August 16, 2017

The NIH established the Kids First Data Resource Center, a pediatric cancer and rare disease data program that will enable clinicians and researchers to collaborate and access multiple genomic datasets.

The resource center — the first of its kind in the pediatric research community — is designed to create a centralized, cloud-based database and discovery portal of clinical and genetic sequence data from various pediatric cancers and structural birth defects cohorts, such as congenital heart defects, hearing loss and cleft palate. The program also will develop analytical tools to provide access to this large-scale data for use in the discovery of novel and improved treatments for children with these conditions.

In the Journals Plus

Older patients with cancer may burden caregivers by overestimating physical abilities

August 14, 2017
Older patients with cancer often reported having better physical function, mental health and social support than their caregivers’ assessments, according to study…

Glioma-related activity in peripheral immune system apparent 5 years before diagnosis

August 11, 2017
Researchers have identified positive and negative associations between five prediagnostic serum cytokines and subsequent glioma diagnosis. Judith Schwartzbaum
In the Journals Plus

Out-of-pocket cancer expenses often exceed patients’ expectations

August 10, 2017
One-third of insured patients with cancer had out-of-pocket costs that exceeded their expectations, according to study results. Underinsured patients faced the greatest…
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Understanding the Clinical Applicability of Integrin Inhibition in the Treatment of Glioblastoma

Integrins play a crucial role in tumor signaling, survival, migration and angiogenesis, making them potent targets for…
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VIDEO: Immune-based therapies ‘rapidly changing’ treatment paradigm for brain metastases

June 3, 2016
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The Patient with Castration-resistant Prostate Cancer

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Castration-resistant prostate cancer (CRPC) is a heterogeneous condition that encompasses a continuum of disease…
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