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Non-small cell lung cancer

Virtual Molecular Tumor Board


Carolinas HealthCare System
Levine Cancer Institute
Presented by: Dr. Kathryn Mileham
Patient: Non-small cell lung cancer

Initial Diagnosis


A 68-year-old female never smoker developed cough that led to a CXR which was without notable abnormality in 2007. Due to lack of resolving symptoms, she underwent additional imaging.

  • 9/17/07: CT chest identified a lobulated right central mass (3.2 x 3.3 cm)

  • 9/26/07: PET/CT confirmed the right upper lobe mass (3.3 x 2.9 cm; mSUV 9.3) and adjacent superior hilar mass (2.5 x 2.2 cm; mSUV 8.0)

  • 10/4/07: Needle core biopsy of RUL mass was pathologically consistent with TTF-1 positive, moderately differentiated adenocarcinoma

  • 11/5/07: Bronchoscopy and mediastinal lymph node biopsy was also pathologically consistent with TTF-1 positive adenocarcinoma

  • T2a N2 M0 stage IIIA non-small cell lung cancer was diagnosed