Modules
Modules
Genomics Primer
Genomics Primer
Overview/Key Objectives
What are Eukaryotic Cells?
DNA Definition
What are Chromosomes?
What is a Genome?
Regulation of Gene Expression in Eukaryotes
Genetic Alterations
References
Assessment Questions
Course Introduction
Course Introduction
Overview/Key Objectives
What is Precision Medicine?
Precision Medicine in the Clinic
Direct-to-Consumer Genomic Testing
Ongoing Genomic Research and Big Data in Precision Medicine
References
Assessment Questions
Pathology Assessment of Tumor Tissue
Pathology Assessment of Tumor Tissue
Overview/Key Objectives
Introduction to the Pathology Laboratory
Specimen Preparation
Initial Pathology Assessment
Common Pathology Tests Performed in Oncology
References
Assessment Questions
Introduction to Liquid Biopsies
Introduction to Liquid Biopsies
Overview/Key Objectives
What is a Liquid Biopsy?
Approaches to Liquid Biopsy Analysis: CTCs and cfDNA
Technologies for Isolation and Detection of CTCs and cfDNA
Liquid Biopsy Applications
Concordance Between Tumor and Liquid Biopsies for Mutational Analysis
Select Commercially Available Liquid Biopsy Assays
References
Assessment Questions
Lung Cancer: Assessment, Treatment
Lung Cancer: Assessment, Treatment
Introduction
Current Oncogenic Biomarkers in Lung Cancer
EGFR Epidermal Growth Factor
EGFR Exon 20 Insertions
EGFR Exon 18
ALK Anaplastic Lymphoma Kinase
ROS1 ROS Proto oncogene 1
BRAF v raf murine sarcoma viral oncogene homolog B
NTRK: Fusion Neurotrophic Tropomyosin Receptor Kinase
MET: Mesenchymal-to-Epithelial Transition
RET Fusion: Rearranged During Transfection
HER2: Human Epidermal Growth Factor 2
KRAS: Kirsten RAT Sarcoma Viral Oncogenic Homolog
References
NTRK3 Fusion
NTRK3 Fusion
Initial Diagnosis
Clinical Progress and Treatment
Imaging
Pathology Part 1
Pathology Part 2
Discussion and Proposed Potential Therapies
References
Whole-Genome Sequencing
Whole-Genome Sequencing
Overview/Key Objectives
What is Whole-Genome Sequencing?
Sanger Sequencing
Whole-Genome Sequencing Methods
Whole-Genome vs. Whole-Exome Sequencing vs. Targeted Sequencing Panels
Strengths and Limitations of Next-Generation Sequencing
Next-Generation Sequencing in the Research and Clinic Settings
Importance of Bioinformatics
References
Assessment Questions
Genomic Medicine in Clinical Practice: Era of Personalized Medicine
Genomic Medicine in Clinical Practice: Era of Personalized Medicine
Overview/Key Objectives
Clinical Settings for Genomic Testing
Considerations When Choosing a Genomic Testing Approach
Liquid Biopsies
Frequently Discussed Topics
Future of Genomic Medicine
References
Assessment Questions
Quizzes
Tumor Boards
Videos
About
Visit Healio.com
Modules
Genomics Primer
Overview/Key Objectives
What are Eukaryotic Cells?
DNA Definition
What are Chromosomes?
What is a Genome?
Regulation of Gene Expression in Eukaryotes
Genetic Alterations
References
Assessment Questions
Course Introduction
Overview/Key Objectives
What is Precision Medicine?
Precision Medicine in the Clinic
Direct-to-Consumer Genomic Testing
Ongoing Genomic Research and Big Data in Precision Medicine
References
Assessment Questions
Pathology Assessment of Tumor Tissue
Overview/Key Objectives
Introduction to the Pathology Laboratory
Specimen Preparation
Initial Pathology Assessment
Common Pathology Tests Performed in Oncology
References
Assessment Questions
Introduction to Liquid Biopsies
Overview/Key Objectives
What is a Liquid Biopsy?
Approaches to Liquid Biopsy Analysis: CTCs and cfDNA
Technologies for Isolation and Detection of CTCs and cfDNA
Liquid Biopsy Applications
Concordance Between Tumor and Liquid Biopsies for Mutational Analysis
Select Commercially Available Liquid Biopsy Assays
References
Assessment Questions
Lung Cancer: Assessment, Treatment
Introduction
Current Oncogenic Biomarkers in Lung Cancer
EGFR Epidermal Growth Factor
EGFR Exon 20 Insertions
EGFR Exon 18
ALK Anaplastic Lymphoma Kinase
ROS1 ROS Proto oncogene 1
BRAF v raf murine sarcoma viral oncogene homolog B
NTRK: Fusion Neurotrophic Tropomyosin Receptor Kinase
MET: Mesenchymal-to-Epithelial Transition
RET Fusion: Rearranged During Transfection
HER2: Human Epidermal Growth Factor 2
KRAS: Kirsten RAT Sarcoma Viral Oncogenic Homolog
References
Whole-Genome Sequencing
Overview/Key Objectives
What is Whole-Genome Sequencing?
Sanger Sequencing
Whole-Genome Sequencing Methods
Whole-Genome vs. Whole-Exome Sequencing vs. Targeted Sequencing Panels
Strengths and Limitations of Next-Generation Sequencing
Next-Generation Sequencing in the Research and Clinic Settings
Importance of Bioinformatics
References
Assessment Questions
Genomic Medicine in Clinical Practice: Era of Personalized Medicine
Overview/Key Objectives
Clinical Settings for Genomic Testing
Considerations When Choosing a Genomic Testing Approach
Liquid Biopsies
Frequently Discussed Topics
Future of Genomic Medicine
References
Assessment Questions
Quizzes
Tumor Boards
Videos
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