Summary of tumor and liquid biopsy concordance
One important issue to consider is whether tumor DNA obtained from liquid biopsy serves as a reliable proxy for mutations identified in tissues. The Table below highlights the results from several studies that sought to interrogate the concordance rates between mutations identified in tissues and liquid biopsies. The results from these studies lend further support to the use of liquid biopsy as an alternative or adjunct to tissue biopsy.
Wafik El-Deiry MD, discusses what cancer types are most appropriate for liquid biopsies.
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