Regular use of NSAIDs significantly improved OS and disease-specific survival among patients with PIK3CA-altered head and neck squamous cell carcinoma, according to results of a prospective study published in Journal of Experimental Medicine.
“Our results suggest that the use of NSAIDs could significantly improve outcomes for not only patients [with head and neck cancer], but also patients with other cancers that contained the PIK3CA mutation,” Jennifer R. Grandis, MD, professor of otolaryngology, head and neck surgery, and member of the Helen Diller Family Comprehensive Cancer Center at University of California, San Francisco, said in a press release. “The magnitude of the apparent advantage is strong and could potentially have a positive impact on human health.”
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